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Peakhood: individual site context extraction for CLIP-seq peak regions

MOTIVATION: CLIP-seq is by far the most widely used method to determine transcriptome-wide binding sites of RNA-binding proteins (RBPs). The binding site locations are identified from CLIP-seq read data by tools termed peak callers. Many RBPs bind to a spliced RNA (i.e. transcript) context, but all...

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Detalles Bibliográficos
Autores principales: Uhl, Michael, Rabsch, Dominik, Eggenhofer, Florian, Backofen, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796379/
https://www.ncbi.nlm.nih.gov/pubmed/34734974
http://dx.doi.org/10.1093/bioinformatics/btab755