COBREXA.jl: constraint-based reconstruction and exascale analysis

SUMMARY: COBREXA.jl is a Julia package for scalable, high-performance constraint-based reconstruction and analysis of very large-scale biological models. Its primary purpose is to facilitate the integration of modern high performance computing environments with the processing and analysis of large-s...

Descripción completa

Detalles Bibliográficos
Autores principales: Kratochvíl, Miroslav, Heirendt, Laurent, Wilken, St Elmo, Pusa, Taneli, Arreckx, Sylvain, Noronha, Alberto, van Aalst, Marvin, Satagopam, Venkata P, Ebenhöh, Oliver, Schneider, Reinhard, Trefois, Christophe, Gu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796381/
https://www.ncbi.nlm.nih.gov/pubmed/34791064
http://dx.doi.org/10.1093/bioinformatics/btab782
Descripción
Sumario:SUMMARY: COBREXA.jl is a Julia package for scalable, high-performance constraint-based reconstruction and analysis of very large-scale biological models. Its primary purpose is to facilitate the integration of modern high performance computing environments with the processing and analysis of large-scale metabolic models of challenging complexity. We report the architecture of the package, and demonstrate how the design promotes analysis scalability on several use-cases with multi-organism community models. AVAILABILITY AND IMPLEMENTATION: https://doi.org/10.17881/ZKCR-BT30. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Ejemplares similares