Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matter

Multiple sclerosis (MS) is a disease of the central nervous system that is characterized by inflammation and focal areas of demyelination, ultimately resulting in axonal degradation and neuronal loss. Several lines of evidence point towards a role for microglia and other brain macrophages in disease...

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Detalles Bibliográficos
Autores principales: Miedema, Anneke, Gerrits, Emma, Brouwer, Nieske, Jiang, Qiong, Kracht, Laura, Meijer, Michel, Nutma, Erik, Peferoen-Baert, Regina, Pijnacker, Anna T. E., Wesseling, Evelyn M., Wijering, Marion H. C., Gabius, Hans-Joachim, Amor, Sandra, Eggen, Bart J. L., Kooistra, Susanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796391/
https://www.ncbi.nlm.nih.gov/pubmed/35090578
http://dx.doi.org/10.1186/s40478-021-01306-3

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