The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo

BACKGROUND: Obesity is caused by the enlargement of the white adipose tissue (WAT) depots, characterized by the hypertrophic enlargement of malfunctioning adipocytes within WAT which increases the storage of triglycerides (TG) in the lipid droplets (LD). Adipogenesis pathways as well as the expressi...

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Detalles Bibliográficos
Autores principales: de Frutos, S., Griera, M., Hatem-Vaquero, M., Campillo, S., Gutiérrez-Calabres, E., García-Ayuso, D., Pardo, M., Calleros, L., Rodríguez-Puyol, M., Rodríguez-Puyol, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796419/
https://www.ncbi.nlm.nih.gov/pubmed/35090553
http://dx.doi.org/10.1186/s13578-022-00746-1

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