Ubiquitinated AIF is a major mediator of hypoxia-induced mitochondrial dysfunction and pulmonary artery smooth muscle cell proliferation

BACKGROUND: Excessive proliferation of pulmonary artery smooth muscle cells (PASMCs) is the main cause of hypoxic pulmonary hypertension (PH), and mitochondrial homeostasis plays a crucial role. However, the specific molecular regulatory mechanism of mitochondrial function in PASMCs remains unclear....

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Detalles Bibliográficos
Autores principales: Ma, Cui, Wang, Xiaoying, He, Siyu, Zhang, Lixin, Bai, June, Qu, Lihui, Qi, Jing, Zheng, Xiaodong, Zhu, Xiangrui, Mei, Jian, Guan, Xiaoyu, Yuan, Hao, Zhu, Daling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796423/
https://www.ncbi.nlm.nih.gov/pubmed/35090552
http://dx.doi.org/10.1186/s13578-022-00744-3

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