FTO suppresses glycolysis and growth of papillary thyroid cancer via decreasing stability of APOE mRNA in an N6-methyladenosine-dependent manner

BACKGROUND: N6-methyladenosine (m(6)A) modification is the most common chemical modification in mammalian mRNAs, and it plays important roles by regulating several cellular processes. Previous studies report that m(6)A is implicated in modulating tumorigenesis and progression. However, dysregulation...

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Detalles Bibliográficos
Autores principales: Huang, Jiapeng, Sun, Wei, Wang, Zhihong, Lv, Chengzhou, Zhang, Ting, Zhang, Dalin, Dong, Wenwu, Shao, Liang, He, Liang, Ji, Xiaoyu, Zhang, Ping, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796435/
https://www.ncbi.nlm.nih.gov/pubmed/35090515
http://dx.doi.org/10.1186/s13046-022-02254-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796435/
https://www.ncbi.nlm.nih.gov/pubmed/35090515
http://dx.doi.org/10.1186/s13046-022-02254-z

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