Cargando…

FTO suppresses glycolysis and growth of papillary thyroid cancer via decreasing stability of APOE mRNA in an N6-methyladenosine-dependent manner

BACKGROUND: N6-methyladenosine (m(6)A) modification is the most common chemical modification in mammalian mRNAs, and it plays important roles by regulating several cellular processes. Previous studies report that m(6)A is implicated in modulating tumorigenesis and progression. However, dysregulation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Jiapeng, Sun, Wei, Wang, Zhihong, Lv, Chengzhou, Zhang, Ting, Zhang, Dalin, Dong, Wenwu, Shao, Liang, He, Liang, Ji, Xiaoyu, Zhang, Ping, Zhang, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796435/ https://www.ncbi.nlm.nih.gov/pubmed/35090515 http://dx.doi.org/10.1186/s13046-022-02254-z

Ejemplares similares

ALKBH5‐induced circular RNA NRIP1 promotes glycolysis in thyroid cancer cells by targeting PKM2
por: Ji, Xiaoyu, et al.
Publicado: (2023)

Comparison of Outcomes Following Thyroid Isthmusectomy, Unilateral Thyroid Lobectomy, and Total Thyroidectomy in Patients with Papillary Thyroid Microcarcinoma of the Thyroid Isthmus: A Retrospective Study at a Single Center
por: Gui, Zhiqiang, et al.
Publicado: (2020)

High Incidence of Distant Metastasis Is Associated With Histopathological Subtype of Pediatric Papillary Thyroid Cancer - a Retrospective Analysis Based on SEER
por: Zeng, Xue, et al.
Publicado: (2021)

RBM47/SNHG5/FOXO3 axis activates autophagy and inhibits cell proliferation in papillary thyroid carcinoma
por: Qin, Yuan, et al.
Publicado: (2022)

Expression Profiles of Circular RNAs in Human Papillary Thyroid Carcinoma Based on RNA Deep Sequencing
por: Lv, Chengzhou, et al.
Publicado: (2021)

N(6)-methyladenosine methyltransferase KIAA1429 elevates colorectal cancer aerobic glycolysis via HK2-dependent manner
por: Li, Ying, et al.
Publicado: (2022)

Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner
por: Wu, Yifei, et al.
Publicado: (2023)

Identification of a Novel Cuproptosis-Related Gene Signature and Integrative Analyses in Thyroid Cancer
por: Huang, Jiapeng, et al.
Publicado: (2023)

LncRNA FTO-IT1 promotes glycolysis and progression of hepatocellular carcinoma through modulating FTO-mediated N6-methyladenosine modification on GLUT1 and PKM2
por: Wang, Fan, et al.
Publicado: (2023)

FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis
por: Zhao, Xu, et al.
Publicado: (2014)

RNA N6-methyladenosine demethylase FTO promotes pancreatic cancer progression by inducing the autocrine activity of PDGFC in an m(6)A-YTHDF2-dependent manner
por: Tan, Zhen, et al.
Publicado: (2022)

Roles of N6‐Methyladenosine Demethylase FTO in Malignant Tumors Progression
por: Zheng, Qing-Kang, et al.
Publicado: (2021)

Analysis of the strategy of LT4 prescribing and TSH monitoring for thyroid carcinoma after lobectomy
por: Wang, Zhihong, et al.
Publicado: (2020)

Nitric oxide inhibits FTO demethylase activity to regulate N(6)-methyladenosine mRNA methylation
por: Kuschman, Hannah Petraitis, et al.
Publicado: (2023)

Risk factors of cervical lymph node metastasis in multifocal papillary thyroid cancer
por: Zhang, Ting, et al.
Publicado: (2022)

Potential Use of 1-25-dihydroxyvitamin D in the Diagnosis and Treatment of Papillary Thyroid Cancer
por: Zhang, Ting, et al.
Publicado: (2018)

N6-methyladenosine demethylase FTO suppressed prostate cancer progression by maintaining CLIC4 mRNA stability
por: Zou, Libin, et al.
Publicado: (2022)

The Differences Between Multifocal and Unifocal Papillary Thyroid Carcinoma in Unilateral Lobe: A Meta-Analysis
por: Zhang, Ting, et al.
Publicado: (2021)

Long non-coding RNA AGAP2-AS1 increases the invasiveness of papillary thyroid cancer
por: Shao, Liang, et al.
Publicado: (2020)

A novel necroptosis-related gene signature associated with immune landscape for predicting the prognosis of papillary thyroid cancer
por: Wang, Zhiyuan, et al.
Publicado: (2022)

HYOU1 facilitates proliferation, invasion and glycolysis of papillary thyroid cancer via stabilizing LDHB mRNA
por: Wang, Jia‐Mei, et al.
Publicado: (2021)

A novel inhibitor of N(6)-methyladenosine demethylase FTO induces mRNA methylation and shows anti-cancer activities
por: Xie, Guoyou, et al.
Publicado: (2022)

N(6)-methyladenosine demethylases Alkbh5/Fto regulate cerebral ischemia-reperfusion injury
por: Xu, Kaiwei, et al.
Publicado: (2020)

N6‐methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO‐PGC‐1α signalling axis
por: Zhuang, Changshui, et al.
Publicado: (2019)

Association between the expression of four upregulated miRNAs and extrathyroidal invasion in papillary thyroid carcinoma
por: Wang, Zhihong, et al.
Publicado: (2013)

RNA N6-methyladenosine demethylase FTO promotes osteoporosis through demethylating Runx2 mRNA and inhibiting osteogenic differentiation
por: Wang, Jing, et al.
Publicado: (2021)

N(6)-Methyladenosine in Nuclear RNA is a Major Substrate of the Obesity-Associated FTO
por: Jia, Guifang, et al.
Publicado: (2011)

MicroRNA-144 inhibits proliferation by targeting WW domain-containing transcription regulator protein 1 in papillary thyroid cancer
por: Sun, Wei, et al.
Publicado: (2018)

miRNA-299-5p regulates estrogen receptor alpha and inhibits migration and invasion of papillary thyroid cancer cell
por: Wang, Zhihong, et al.
Publicado: (2018)

RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3
por: Niu, Yi, et al.
Publicado: (2019)

Circular RNAs Regulate Glucose Metabolism in Cancer Cells
por: Ji, Xiaoyu, et al.
Publicado: (2021)

IL‐34 is a potential biomarker for the treatment of papillary thyroid cancer
por: Zhang, Ping, et al.
Publicado: (2020)

Surgery After Ultrasound-Guided Radiofrequency Ablation for Papillary Thyroid Carcinoma in 21 Patients: A Retrospective Study from a Single Center in China
por: Sun, Wei, et al.
Publicado: (2020)

Risk Factors for Central Lymph Node Metastasis in CN0 Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis
por: Sun, Wei, et al.
Publicado: (2015)

Estrogen Induces Metastatic Potential of Papillary Thyroid Cancer Cells through Estrogen Receptor α and β
por: Dong, Wenwu, et al.
Publicado: (2013)

Calcitriol enhances Doxorubicin‐induced apoptosis in papillary thyroid carcinoma cells via regulating VDR/PTPN2/p‐STAT3 pathway
por: Zhang, Ting, et al.
Publicado: (2020)

APOE Is a Prognostic Biomarker and Correlates with Immune Infiltrates in Papillary Thyroid Carcinoma
por: Lin, Xu, et al.
Publicado: (2022)

MMP24 Contributes to Neuropathic Pain in an FTO-Dependent Manner in the Spinal Cord Neurons
por: Ma, Longfei, et al.
Publicado: (2021)

The NEAT1_2/miR-491 Axis Modulates Papillary Thyroid Cancer Invasion and Metastasis Through TGM2/NFκb/FN1 Signaling
por: Sun, Wei, et al.
Publicado: (2021)

Pan-Cancer Analysis of the N6-Methyladenosine Eraser FTO as a Potential Prognostic and Immunological Biomarker
por: Zhao, Chengwen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3bkn55q2e8ndf37a2864mtfoqk