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Novel bi-allelic MSH4 variants causes meiotic arrest and non-obstructive azoospermia

BACKGROUND: Non-obstructive azoospermia (NOA) is one of the most severe type in male infertility, and the genetic causes of NOA with meiotic arrest remain elusive. METHODS: Four Chinese families with NOA participated in the study. We performed whole-exome sequencing (WES) for the four NOA-affected p...

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Detalles Bibliográficos
Autores principales:	Li, Peng, Ji, Zhiyong, Zhi, Erlei, Zhang, Yuxiang, Han, Sha, Zhao, Liangyu, Tian, Ruhui, Chen, Huixing, Huang, Yuhua, Zhang, Jing, Chen, Huirong, Zhao, Fujun, Zhou, Zhi, Li, Zheng, Yao, Chencheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796546/ https://www.ncbi.nlm.nih.gov/pubmed/35090489 http://dx.doi.org/10.1186/s12958-022-00900-x

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