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LncRNA ZFAS1 regulates the proliferation, oxidative stress, fibrosis, and inflammation of high glucose-induced human mesangial cells via the miR-588/ROCK1 axis

BACKGROUND: Diabetic nephropathy (DN) is a critical and the most common microvascular complication and its pathogenesis is still faintly understood. Thus, this study was performed to examine the long non-coding RNA ZNFX1 Antisense Gene Protein 1 (lncRNA ZFAS1) biological function and mechanism of re...

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Detalles Bibliográficos
Autores principales: Geng, Zhuang, Dong, Bingzi, Lv, Wenshan, Wang, Zhongchao, Wang, Xiang, Huang, YaJing, Wang, Yangang, Xu, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796624/
https://www.ncbi.nlm.nih.gov/pubmed/35090549
http://dx.doi.org/10.1186/s13098-022-00791-3