Pulmonary infection by SARS-CoV-2 induces senescence accompanied by an inflammatory phenotype in severe COVID-19: possible implications for viral mutagenesis

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of the respiratory system can progress to a multisystemic disease with aberrant inflammatory response. Cellular senescence promotes chronic inflammation, named senescence-associated secretory phenotype (SASP). We inve...

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Detalles Bibliográficos
Autores principales: Evangelou, Konstantinos, Veroutis, Dimitris, Paschalaki, Koralia, Foukas, Periklis G., Lagopati, Nefeli, Dimitriou, Marios, Papaspyropoulos, Angelos, Konda, Bindu, Hazapis, Orsalia, Polyzou, Aikaterini, Havaki, Sophia, Kotsinas, Athanassios, Kittas, Christos, Tzioufas, Athanasios G., de Leval, Laurence, Vassilakos, Demetris, Tsiodras, Sotirios, Stripp, Barry R., Papantonis, Argyris, Blandino, Giovanni, Karakasiliotis, Ioannis, Barnes, Peter J., Gorgoulis, Vassilis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796696/
https://www.ncbi.nlm.nih.gov/pubmed/35086840
http://dx.doi.org/10.1183/13993003.02951-2021

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