Solid papillary carcinoma of the breast

Solid Papillary Carcinoma (SPC) of the breast is a rare tumor with an incidence of less than 1%, mainly affecting elderly females. It is morphologically characterized by well-defined nodules with low-grade nuclear features associated with fibrovascular cores and shows neuroendocrine differentiation....

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Autores principales: Jadhav, Toyaja, Prasad, Shashi Shekhar, Guleria, Bhupesh, Tevatia, Manvir Singh, Guleria, Prerna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital Universitário da Universidade de São Paulo 2022
Materias:
Clinical Case Report and Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796863/
https://www.ncbi.nlm.nih.gov/pubmed/35096664
http://dx.doi.org/10.4322/acr.2021.352
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author Jadhav, Toyaja
Prasad, Shashi Shekhar
Guleria, Bhupesh
Tevatia, Manvir Singh
Guleria, Prerna
author_facet Jadhav, Toyaja
Prasad, Shashi Shekhar
Guleria, Bhupesh
Tevatia, Manvir Singh
Guleria, Prerna
author_sort Jadhav, Toyaja
collection PubMed
description Solid Papillary Carcinoma (SPC) of the breast is a rare tumor with an incidence of less than 1%, mainly affecting elderly females. It is morphologically characterized by well-defined nodules with low-grade nuclear features associated with fibrovascular cores and shows neuroendocrine differentiation. SPC can be in-situ or invasive but has a favorable prognosis. It is a morphological mimicker of some pre-malignant conditions leading to its frequent misdiagnosis. An appropriate immunohistochemical (IHC) panel workup helps in distinguishing this tumor from its various morphological mimics. In this report, we present one such case of SPC with a small focus of invasion, reviewing the literature.
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spelling pubmed-87968632022-01-29 Solid papillary carcinoma of the breast Jadhav, Toyaja Prasad, Shashi Shekhar Guleria, Bhupesh Tevatia, Manvir Singh Guleria, Prerna Autops Case Rep Clinical Case Report and Review Solid Papillary Carcinoma (SPC) of the breast is a rare tumor with an incidence of less than 1%, mainly affecting elderly females. It is morphologically characterized by well-defined nodules with low-grade nuclear features associated with fibrovascular cores and shows neuroendocrine differentiation. SPC can be in-situ or invasive but has a favorable prognosis. It is a morphological mimicker of some pre-malignant conditions leading to its frequent misdiagnosis. An appropriate immunohistochemical (IHC) panel workup helps in distinguishing this tumor from its various morphological mimics. In this report, we present one such case of SPC with a small focus of invasion, reviewing the literature. Hospital Universitário da Universidade de São Paulo 2022-01-13 /pmc/articles/PMC8796863/ /pubmed/35096664 http://dx.doi.org/10.4322/acr.2021.352 Text en Copyright © 2022 The Author(s). https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Case Report and Review
Jadhav, Toyaja
Prasad, Shashi Shekhar
Guleria, Bhupesh
Tevatia, Manvir Singh
Guleria, Prerna
Solid papillary carcinoma of the breast
title Solid papillary carcinoma of the breast
title_full Solid papillary carcinoma of the breast
title_fullStr Solid papillary carcinoma of the breast
title_full_unstemmed Solid papillary carcinoma of the breast
title_short Solid papillary carcinoma of the breast
title_sort solid papillary carcinoma of the breast
topic Clinical Case Report and Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796863/
https://www.ncbi.nlm.nih.gov/pubmed/35096664
http://dx.doi.org/10.4322/acr.2021.352
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