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Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas

Splenic tuberculosis and Pott´s disease are two rare entities, in particular in immunocompetent people. We here report the case of a 57-year-old immunocompetent woman presenting with atypical pain in the left hypochondriac region evolving over the last 3 months, associated with lower limb paraparesi...

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Autores principales: N´khaili, Asmaa, Jarti, Mariama, Haida, Marj Zouhour, Aouroud, Meryem, Errami, Adil Ait, Oubaha, Sofia, Samlani, Zouhour, Krati, Khadija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797038/
https://www.ncbi.nlm.nih.gov/pubmed/35145592
http://dx.doi.org/10.11604/pamj.2021.40.230.32257
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author N´khaili, Asmaa
Jarti, Mariama
Haida, Marj Zouhour
Aouroud, Meryem
Errami, Adil Ait
Oubaha, Sofia
Samlani, Zouhour
Krati, Khadija
author_facet N´khaili, Asmaa
Jarti, Mariama
Haida, Marj Zouhour
Aouroud, Meryem
Errami, Adil Ait
Oubaha, Sofia
Samlani, Zouhour
Krati, Khadija
author_sort N´khaili, Asmaa
collection PubMed
description Splenic tuberculosis and Pott´s disease are two rare entities, in particular in immunocompetent people. We here report the case of a 57-year-old immunocompetent woman presenting with atypical pain in the left hypochondriac region evolving over the last 3 months, associated with lower limb paraparesis with progressive onset. Laboratory data did not provide any specific information regarding diagnosis, except for positive response to the QuantiFERON Test. Abdominal and pelvic computed tomography (CT) scan showed splenomegaly with multiple nodular, hypodense lesions in the spleen. Spinal cord magnetic resonance imaging (MRI) showed spondyldiscitis at the D10/D11 level with epidural and paravertebral collections responsible for medullary compression. GeneXpert assay on bone biopsy was positive and histological examination objectified granuloma characterized by the presence of central caseous necrosis. The diagnosis of multifocal tuberculosis was retained.
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spelling pubmed-87970382022-02-09 Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas N´khaili, Asmaa Jarti, Mariama Haida, Marj Zouhour Aouroud, Meryem Errami, Adil Ait Oubaha, Sofia Samlani, Zouhour Krati, Khadija Pan Afr Med J Case Report Splenic tuberculosis and Pott´s disease are two rare entities, in particular in immunocompetent people. We here report the case of a 57-year-old immunocompetent woman presenting with atypical pain in the left hypochondriac region evolving over the last 3 months, associated with lower limb paraparesis with progressive onset. Laboratory data did not provide any specific information regarding diagnosis, except for positive response to the QuantiFERON Test. Abdominal and pelvic computed tomography (CT) scan showed splenomegaly with multiple nodular, hypodense lesions in the spleen. Spinal cord magnetic resonance imaging (MRI) showed spondyldiscitis at the D10/D11 level with epidural and paravertebral collections responsible for medullary compression. GeneXpert assay on bone biopsy was positive and histological examination objectified granuloma characterized by the presence of central caseous necrosis. The diagnosis of multifocal tuberculosis was retained. The African Field Epidemiology Network 2021-12-16 /pmc/articles/PMC8797038/ /pubmed/35145592 http://dx.doi.org/10.11604/pamj.2021.40.230.32257 Text en Copyright: Asmaa N’khaili et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
N´khaili, Asmaa
Jarti, Mariama
Haida, Marj Zouhour
Aouroud, Meryem
Errami, Adil Ait
Oubaha, Sofia
Samlani, Zouhour
Krati, Khadija
Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas
title Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas
title_full Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas
title_fullStr Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas
title_full_unstemmed Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas
title_short Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas
title_sort splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797038/
https://www.ncbi.nlm.nih.gov/pubmed/35145592
http://dx.doi.org/10.11604/pamj.2021.40.230.32257
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