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Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas
Splenic tuberculosis and Pott´s disease are two rare entities, in particular in immunocompetent people. We here report the case of a 57-year-old immunocompetent woman presenting with atypical pain in the left hypochondriac region evolving over the last 3 months, associated with lower limb paraparesi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797038/ https://www.ncbi.nlm.nih.gov/pubmed/35145592 http://dx.doi.org/10.11604/pamj.2021.40.230.32257 |
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author | N´khaili, Asmaa Jarti, Mariama Haida, Marj Zouhour Aouroud, Meryem Errami, Adil Ait Oubaha, Sofia Samlani, Zouhour Krati, Khadija |
author_facet | N´khaili, Asmaa Jarti, Mariama Haida, Marj Zouhour Aouroud, Meryem Errami, Adil Ait Oubaha, Sofia Samlani, Zouhour Krati, Khadija |
author_sort | N´khaili, Asmaa |
collection | PubMed |
description | Splenic tuberculosis and Pott´s disease are two rare entities, in particular in immunocompetent people. We here report the case of a 57-year-old immunocompetent woman presenting with atypical pain in the left hypochondriac region evolving over the last 3 months, associated with lower limb paraparesis with progressive onset. Laboratory data did not provide any specific information regarding diagnosis, except for positive response to the QuantiFERON Test. Abdominal and pelvic computed tomography (CT) scan showed splenomegaly with multiple nodular, hypodense lesions in the spleen. Spinal cord magnetic resonance imaging (MRI) showed spondyldiscitis at the D10/D11 level with epidural and paravertebral collections responsible for medullary compression. GeneXpert assay on bone biopsy was positive and histological examination objectified granuloma characterized by the presence of central caseous necrosis. The diagnosis of multifocal tuberculosis was retained. |
format | Online Article Text |
id | pubmed-8797038 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-87970382022-02-09 Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas N´khaili, Asmaa Jarti, Mariama Haida, Marj Zouhour Aouroud, Meryem Errami, Adil Ait Oubaha, Sofia Samlani, Zouhour Krati, Khadija Pan Afr Med J Case Report Splenic tuberculosis and Pott´s disease are two rare entities, in particular in immunocompetent people. We here report the case of a 57-year-old immunocompetent woman presenting with atypical pain in the left hypochondriac region evolving over the last 3 months, associated with lower limb paraparesis with progressive onset. Laboratory data did not provide any specific information regarding diagnosis, except for positive response to the QuantiFERON Test. Abdominal and pelvic computed tomography (CT) scan showed splenomegaly with multiple nodular, hypodense lesions in the spleen. Spinal cord magnetic resonance imaging (MRI) showed spondyldiscitis at the D10/D11 level with epidural and paravertebral collections responsible for medullary compression. GeneXpert assay on bone biopsy was positive and histological examination objectified granuloma characterized by the presence of central caseous necrosis. The diagnosis of multifocal tuberculosis was retained. The African Field Epidemiology Network 2021-12-16 /pmc/articles/PMC8797038/ /pubmed/35145592 http://dx.doi.org/10.11604/pamj.2021.40.230.32257 Text en Copyright: Asmaa N’khaili et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report N´khaili, Asmaa Jarti, Mariama Haida, Marj Zouhour Aouroud, Meryem Errami, Adil Ait Oubaha, Sofia Samlani, Zouhour Krati, Khadija Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas |
title | Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas |
title_full | Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas |
title_fullStr | Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas |
title_full_unstemmed | Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas |
title_short | Splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas |
title_sort | splénomégalie multi-nodulaire révélatrice d’une tuberculose multifocale à localisation splénique et vertébrale: à propos d’un cas |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797038/ https://www.ncbi.nlm.nih.gov/pubmed/35145592 http://dx.doi.org/10.11604/pamj.2021.40.230.32257 |
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