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Multi‐omic landscaping of human midbrains identifies disease‐relevant molecular targets and pathways in advanced‐stage Parkinson's disease

BACKGROUND: Parkinson's disease (PD) is the second most common neurodegenerative disorder whose prevalence is rapidly increasing worldwide. The molecular mechanisms underpinning the pathophysiology of sporadic PD remain incompletely understood. Therefore, causative therapies are still elusive....

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Detalles Bibliográficos
Autores principales: Caldi Gomes, Lucas, Galhoz, Ana, Jain, Gaurav, Roser, Anna‐Elisa, Maass, Fabian, Carboni, Eleonora, Barski, Elisabeth, Lenz, Christof, Lohmann, Katja, Klein, Christine, Bähr, Mathias, Fischer, André, Menden, Michael P., Lingor, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797064/
https://www.ncbi.nlm.nih.gov/pubmed/35090094
http://dx.doi.org/10.1002/ctm2.692