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Transcription factor specificity limits the number of DNA-binding motifs

We study the limits imposed by transcription factor specificity on the maximum number of binding motifs that can coexist in a gene regulatory network, using the SwissRegulon Fantom5 collection of 684 human transcription factor binding sites as a model. We describe transcription factor specificity us...

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Detalles Bibliográficos
Autores principales:	Aptekmann, Ariel A., Bulavka, Denys, Nadra, Alejandro D., Sánchez, Ignacio E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797260/ https://www.ncbi.nlm.nih.gov/pubmed/35089985 http://dx.doi.org/10.1371/journal.pone.0263307

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