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HIF2A overexpression reduces cisplatin sensitivity in cervical cancer by inducing excessive autophagy

BACKGROUND: Hypoxia-induced autophagy is a crucial factor that induces chemotherapy resistance in tumor cells. As a key regulator facilitating the adaptation of solid tumors to hypoxia, the role of hypoxia-inducible factors (HIFs) in regulating hypoxia-induced chemotherapy resistance and autophagy h...

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Detalles Bibliográficos
Autores principales: Jiang, Lixia, Xia, Yu, Zhong, Tianyu, Zhang, Huijuan, Jin, Qing, Li, Feng, Shi, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797276/
https://www.ncbi.nlm.nih.gov/pubmed/35117160
http://dx.doi.org/10.21037/tcr.2019.11.17