Cargando…

HIF2A overexpression reduces cisplatin sensitivity in cervical cancer by inducing excessive autophagy

BACKGROUND: Hypoxia-induced autophagy is a crucial factor that induces chemotherapy resistance in tumor cells. As a key regulator facilitating the adaptation of solid tumors to hypoxia, the role of hypoxia-inducible factors (HIFs) in regulating hypoxia-induced chemotherapy resistance and autophagy h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Lixia, Xia, Yu, Zhong, Tianyu, Zhang, Huijuan, Jin, Qing, Li, Feng, Shi, Shaohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797276/ https://www.ncbi.nlm.nih.gov/pubmed/35117160 http://dx.doi.org/10.21037/tcr.2019.11.17

Ejemplares similares

MicroRNA-519d-3p Inhibits Proliferation and Promotes Apoptosis by Targeting HIF-2α in Cervical Cancer Under Hypoxic Conditions
por: Jiang, Lixia, et al.
Publicado: (2018)

The role of HIF-1α in chemo-/radioresistant tumors
por: Xia, Yu, et al.
Publicado: (2018)

TIMP3 Overexpression Improves the Sensitivity of Osteosarcoma to Cisplatin by Reducing IL-6 Production
por: Han, Xiu-guo, et al.
Publicado: (2018)

Protein kinase C β inhibits autophagy and sensitizes cervical cancer Hela cells to cisplatin
por: Li, Na, et al.
Publicado: (2017)

TAK1 mediates excessive autophagy via p38 and ERK in cisplatin‐induced acute kidney injury
por: Zhou, Jun, et al.
Publicado: (2018)

Overexpression of HIF Prolyl-Hydoxylase-2 transgene in the renal medulla induced a salt sensitive hypertension
por: Zhu, Qing, et al.
Publicado: (2012)

Autophagy Induced by HIF1α Overexpression Supports Trophoblast Invasion by Supplying Cellular Energy
por: Yamanaka-Tatematsu, Mikiko, et al.
Publicado: (2013)

NHERF1 Enhances Cisplatin Sensitivity in Human Cervical Cancer Cells
por: Tao, Tao, et al.
Publicado: (2017)

Platinum sensitivity and non-cross-resistance of cisplatin analogue with cisplatin in recurrent cervical cancer
por: Takekuma, Munetaka, et al.
Publicado: (2015)

Knockdown of THOC1 reduces the proliferation of hepatocellular carcinoma and increases the sensitivity to cisplatin
por: Cai, Shijiao, et al.
Publicado: (2020)

NRBP2 Overexpression Inhibits Cell Proliferation and Migration and Increases Cisplatin Sensitivity in Intrahepatic Cholangiocarcinoma
por: Li, Xiaopeng, et al.
Publicado: (2017)

Overexpression of IL-7 enhances cisplatin resistance in glioma
por: Cui, Lei, et al.
Publicado: (2012)

Overexpression of HOTAIR leads to radioresistance of human cervical cancer via promoting HIF-1α expression
por: Li, Ning, et al.
Publicado: (2018)

Lysophosphatidic acid exerts protective effects on HEI-OC1 cells against cytotoxicity of cisplatin by decreasing apoptosis, excessive autophagy, and accumulation of ROS
por: An, Xiaogang, et al.
Publicado: (2023)

Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells
por: Yu, Le, et al.
Publicado: (2016)

Excessive mechanical stress-induced intervertebral disc degeneration is related to Piezo1 overexpression triggering the imbalance of autophagy/apoptosis in human nucleus pulpous
por: Shi, Sheng, et al.
Publicado: (2022)

Enhancement of Cisplatin Sensitivity in Human Cervical Cancer: Epigallocatechin-3-Gallate
por: Kilic, Ulkan, et al.
Publicado: (2015)

Expression of HIF-2α and VEGF in Cervical Squamous Cell Carcinoma and Its Clinical Significance
por: Zhang, Lixia, et al.
Publicado: (2016)

Overexpression of xeroderma pigmentosum group C decreases the chemotherapeutic sensitivity of colorectal carcinoma cells to cisplatin
por: Zhang, Yi, et al.
Publicado: (2018)

Nestin overexpression reduces the sensitivity of gastric cancer cells to trastuzumab
por: Wei, Yi-Chou, et al.
Publicado: (2023)

Autophagy inhibition impairs the epithelial-mesenchymal transition and enhances cisplatin sensitivity in nasopharyngeal carcinoma
por: Su, Zhongwu, et al.
Publicado: (2017)

Overexpression of bHLH domain of HIF-1 failed to inhibit the HIF-1 transcriptional activity in hypoxia
por: Sadeghi, Fatemeh, et al.
Publicado: (2020)

Meclofenamic Acid Reduces Reactive Oxygen Species Accumulation and Apoptosis, Inhibits Excessive Autophagy, and Protects Hair Cell-Like HEI-OC1 Cells From Cisplatin-Induced Damage
por: Li, He, et al.
Publicado: (2018)

HIF in Nephrotoxicity during Cisplatin Chemotherapy: Regulation, Function and Therapeutic Potential
por: Li, Siyao, et al.
Publicado: (2021)

Corrigendum to “Expression of HIF-2α and VEGF in Cervical Squamous Cell Carcinoma and Its Clinical Significance”
por: Zhang, Lixia, et al.
Publicado: (2017)

Overexpression of carbonic anhydrase and HIF-1α in Wilms tumours
por: Dungwa, Josiah V, et al.
Publicado: (2011)

Saturated hydrogen saline ameliorates lipopolysaccharide-induced acute lung injury by reducing excessive autophagy
por: Liu, Yiming, et al.
Publicado: (2017)

Overexpression of the Survivin gene in SGC7901 cell resistance to cisplatin
por: DONG, HANZHANG, et al.
Publicado: (2014)

Galectin-1 overexpression promotes progression and chemoresistance to cisplatin in epithelial ovarian cancer
por: Zhang, P, et al.
Publicado: (2014)

Inhibition of HIF1A-AS1 promoted starvation-induced hepatocellular carcinoma cell apoptosis by reducing HIF-1α/mTOR-mediated autophagy
por: Hong, Fenfen, et al.
Publicado: (2020)

Interaction between p53 and Ras signaling controls cisplatin resistance via HDAC4- and HIF-1α-mediated regulation of apoptosis and autophagy
por: Zhang, Xiaofei, et al.
Publicado: (2019)

Panax notoginseng saponins mitigate cisplatin induced nephrotoxicity by inducing mitophagy via HIF-1α
por: Liang, Xueyan, et al.
Publicado: (2017)

Chloroquine enhances the efficacy of cisplatin by suppressing autophagy in human adrenocortical carcinoma treatment
por: Qin, Liang, et al.
Publicado: (2016)

Pentoxifylline Sensitizes Cisplatin-Resistant Human Cervical Cancer Cells to Cisplatin Treatment: Involvement of Mitochondrial and NF-Kappa B Pathways
por: Bravo-Cuellar, Alejandro, et al.
Publicado: (2020)

Autophagy inhibitor chloroquine increases sensitivity to cisplatin in QBC939 cholangiocarcinoma cells by mitochondrial ROS
por: Qu, Xianzhi, et al.
Publicado: (2017)

YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC
por: Cui, Yanwei, et al.
Publicado: (2020)

iASPP overexpression is associated with clinical outcome in spinal chordoma and influences cellular proliferation, invasion, and sensitivity to cisplatin in vitro
por: Ma, Yunlong, et al.
Publicado: (2017)

Knockdown of ST6Gal-I increases cisplatin sensitivity in cervical cancer cells
por: Zhang, Xiaopeng, et al.
Publicado: (2016)

Bixin and fucoxanthin sensitize human lung cancer and cervical cancer cell to cisplatin in vitro
por: Nurcahyanti, Agustina Dwi Retno, et al.
Publicado: (2021)

EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer
por: Wang, Xuemin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_bg3lh1e778ea7oi5utqr5r5klv