Cargando…

A review of the research progress in T-lymphocyte immunity and cervical cancer

Cervical cancer develops as a result of T-cell immune evasion by human papillomavirus (HPV). T-cell immunity requires the participation of many factors, such as antigen-presenting cells (APCs), cytokines, co-stimulatory molecules, etc. HPV vaccines are promising treatments to prevent HPV infection a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Lina, Mao, Zhilei, Lai, Yiqing, Wan, Ting, Zhang, Keliang, Zhou, Beibei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797462/
https://www.ncbi.nlm.nih.gov/pubmed/35117549
http://dx.doi.org/10.21037/tcr.2020.01.33
Descripción
Sumario:Cervical cancer develops as a result of T-cell immune evasion by human papillomavirus (HPV). T-cell immunity requires the participation of many factors, such as antigen-presenting cells (APCs), cytokines, co-stimulatory molecules, etc. HPV vaccines are promising treatments to prevent HPV infection and cervical cancer. This article mainly provides a summary of the number and function changes of T cells during HPV infection and cervical cancer development. Studies on t-cell immunotherapy, which is expected to become a new treatment for cervical cancer after surgery, radiotherapy, and chemotherapy, are also reviewed in this article.