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A review of the research progress in T-lymphocyte immunity and cervical cancer
Cervical cancer develops as a result of T-cell immune evasion by human papillomavirus (HPV). T-cell immunity requires the participation of many factors, such as antigen-presenting cells (APCs), cytokines, co-stimulatory molecules, etc. HPV vaccines are promising treatments to prevent HPV infection a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797462/ https://www.ncbi.nlm.nih.gov/pubmed/35117549 http://dx.doi.org/10.21037/tcr.2020.01.33 |
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author | Zhang, Lina Mao, Zhilei Lai, Yiqing Wan, Ting Zhang, Keliang Zhou, Beibei |
author_facet | Zhang, Lina Mao, Zhilei Lai, Yiqing Wan, Ting Zhang, Keliang Zhou, Beibei |
author_sort | Zhang, Lina |
collection | PubMed |
description | Cervical cancer develops as a result of T-cell immune evasion by human papillomavirus (HPV). T-cell immunity requires the participation of many factors, such as antigen-presenting cells (APCs), cytokines, co-stimulatory molecules, etc. HPV vaccines are promising treatments to prevent HPV infection and cervical cancer. This article mainly provides a summary of the number and function changes of T cells during HPV infection and cervical cancer development. Studies on t-cell immunotherapy, which is expected to become a new treatment for cervical cancer after surgery, radiotherapy, and chemotherapy, are also reviewed in this article. |
format | Online Article Text |
id | pubmed-8797462 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-87974622022-02-02 A review of the research progress in T-lymphocyte immunity and cervical cancer Zhang, Lina Mao, Zhilei Lai, Yiqing Wan, Ting Zhang, Keliang Zhou, Beibei Transl Cancer Res Review Article Cervical cancer develops as a result of T-cell immune evasion by human papillomavirus (HPV). T-cell immunity requires the participation of many factors, such as antigen-presenting cells (APCs), cytokines, co-stimulatory molecules, etc. HPV vaccines are promising treatments to prevent HPV infection and cervical cancer. This article mainly provides a summary of the number and function changes of T cells during HPV infection and cervical cancer development. Studies on t-cell immunotherapy, which is expected to become a new treatment for cervical cancer after surgery, radiotherapy, and chemotherapy, are also reviewed in this article. AME Publishing Company 2020-03 /pmc/articles/PMC8797462/ /pubmed/35117549 http://dx.doi.org/10.21037/tcr.2020.01.33 Text en 2020 Translational Cancer Research. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/. |
spellingShingle | Review Article Zhang, Lina Mao, Zhilei Lai, Yiqing Wan, Ting Zhang, Keliang Zhou, Beibei A review of the research progress in T-lymphocyte immunity and cervical cancer |
title | A review of the research progress in T-lymphocyte immunity and cervical cancer |
title_full | A review of the research progress in T-lymphocyte immunity and cervical cancer |
title_fullStr | A review of the research progress in T-lymphocyte immunity and cervical cancer |
title_full_unstemmed | A review of the research progress in T-lymphocyte immunity and cervical cancer |
title_short | A review of the research progress in T-lymphocyte immunity and cervical cancer |
title_sort | review of the research progress in t-lymphocyte immunity and cervical cancer |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797462/ https://www.ncbi.nlm.nih.gov/pubmed/35117549 http://dx.doi.org/10.21037/tcr.2020.01.33 |
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