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Targeting COX-2 potently inhibits proliferation of cancer cells in vivo but not in vitro in cutaneous squamous cell carcinoma

BACKGROUND: Cyclooxygenase 2 (COX-2) is an inducible enzyme which promotes tumorigenesis in many types of cancers. Genetic knockout of COX-2 significantly suppresses the tumorigenesis of skin squamous cell carcinoma (SCC). However, COX-2 inhibitor treatment only showed mild to moderate inhibition on...

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Detalles Bibliográficos
Autores principales:	Gao, Lipeng, Wang, Tim Hua, Chen, Champ Peng, Xiang, Jan Jian, Zhao, Xu-Bo, Gui, Rong-Yin, Liao, Xin-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797700/ https://www.ncbi.nlm.nih.gov/pubmed/35116540 http://dx.doi.org/10.21037/tcr-20-3527

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