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Modulating environmental signals to reveal mechanisms and vulnerabilities of cancer persisters

Cancer persister cells are able to survive otherwise lethal doses of drugs through nongenetic mechanisms, which can lead to cancer regrowth and drug resistance. The broad spectrum of molecular differences observed between persisters and their treatment-naïve counterparts makes it challenging to iden...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoxiao, Bieber, Jake M., Hammerlindl, Heinz, Chalkley, Robert J., Li, Kathy H., Burlingame, Alma L., Jacobson, Matthew P., Wu, Lani F., Altschuler, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797778/
https://www.ncbi.nlm.nih.gov/pubmed/35089788
http://dx.doi.org/10.1126/sciadv.abi7711

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