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Modulating environmental signals to reveal mechanisms and vulnerabilities of cancer persisters
Cancer persister cells are able to survive otherwise lethal doses of drugs through nongenetic mechanisms, which can lead to cancer regrowth and drug resistance. The broad spectrum of molecular differences observed between persisters and their treatment-naïve counterparts makes it challenging to iden...
Autores principales: | Sun, Xiaoxiao, Bieber, Jake M., Hammerlindl, Heinz, Chalkley, Robert J., Li, Kathy H., Burlingame, Alma L., Jacobson, Matthew P., Wu, Lani F., Altschuler, Steven J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797778/ https://www.ncbi.nlm.nih.gov/pubmed/35089788 http://dx.doi.org/10.1126/sciadv.abi7711 |
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