Curcumin reverses the sunitinib resistance in clear cell renal cell carcinoma (ccRCC) through the induction of ferroptosis via the ADAMTS18 gene

BACKGROUND: To explore the possible mechanism by which curcumin reverses the sunitinib resistance in clear cell renal cell carcinoma (ccRCC). METHODS: A sunitinib-resistant ccRCC cell model was established. The MTT assay was used to determine the half maximal inhibitory concentration (IC(50)) and dr...

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Detalles Bibliográficos
Autores principales: Xu, Ben, Zhu, Wei-Jie, Peng, Yi-Ji, Cheng, Si-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797884/
https://www.ncbi.nlm.nih.gov/pubmed/35116623
http://dx.doi.org/10.21037/tcr-21-227

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