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A positive feedback loop formed by NGFR and FOXP3 contributes to the resistance of non-small cell lung cancer to icotinib

BACKGROUND: The study was aimed to investigate the mechanisms causing acquired chemoresistance to icotinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), in non-small cell lung cancer (NSCLC). METHODS: Three wildtype NSCLC cell lines were used to produce icotinib-resistan...

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Detalles Bibliográficos
Autores principales: Huang, Jun, Yu, Qiuhua, Zhou, Yanjuan, Chu, Ying, Jiang, Feng, Zhu, Xiaobo, Zhang, Junjie, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797958/
https://www.ncbi.nlm.nih.gov/pubmed/35117449
http://dx.doi.org/10.21037/tcr.2019.12.60