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A positive feedback loop formed by NGFR and FOXP3 contributes to the resistance of non-small cell lung cancer to icotinib
BACKGROUND: The study was aimed to investigate the mechanisms causing acquired chemoresistance to icotinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), in non-small cell lung cancer (NSCLC). METHODS: Three wildtype NSCLC cell lines were used to produce icotinib-resistan...
Autores principales: | Huang, Jun, Yu, Qiuhua, Zhou, Yanjuan, Chu, Ying, Jiang, Feng, Zhu, Xiaobo, Zhang, Junjie, Wang, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797958/ https://www.ncbi.nlm.nih.gov/pubmed/35117449 http://dx.doi.org/10.21037/tcr.2019.12.60 |
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