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Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging

Advancing age causes reduced hippocampal neurogenesis, associated with age-related cognitive decline. The spatial relationship of age-induced alterations in neural stem cells (NSCs) and surrounding cells within the hippocampal niche remains poorly understood due to limitations of antibody-based cell...

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Detalles Bibliográficos
Autores principales: Cole, John Darby, Sarabia del Castillo, Jacobo, Gut, Gabriele, Gonzalez-Bohorquez, Daniel, Pelkmans, Lucas, Jessberger, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798039/
https://www.ncbi.nlm.nih.gov/pubmed/35089129
http://dx.doi.org/10.7554/eLife.68000