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SSNA1 stabilizes dynamic microtubules and detects microtubule damage

Sjögren’s syndrome nuclear autoantigen-1 (SSNA1/NA14) is a microtubule-associated protein with important functions in cilia, dividing cells, and developing neurons. However, the direct effects of SSNA1 on microtubules are not known. We employed in vitro reconstitution with purified proteins and TIRF...

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Detalles Bibliográficos
Autores principales: Lawrence, Elizabeth J, Arpag, Goker, Arnaiz, Cayetana, Zanic, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798045/
https://www.ncbi.nlm.nih.gov/pubmed/34970964
http://dx.doi.org/10.7554/eLife.67282