Solamargine inhibits proliferation and promotes apoptosis of CM-319 human chordoma cells through suppression of notch pathway

BACKGROUND: Solamargine (SM), which represents a natural steroid alkaloid glycoside compound and a cytotoxic agent, has been proved to enhance the sensitivity of lung cancer cells to tumor necrosis factors (TNFs). In this study, we aimed to investigate the roles and mechanisms of SM in chordoma. MET...

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Detalles Bibliográficos
Autores principales: Liu, Junqi, Wang, Zhenlin, Xu, Cong, Qi, Yan, Zhang, Qiuhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798112/
https://www.ncbi.nlm.nih.gov/pubmed/35116783
http://dx.doi.org/10.21037/tcr.2019.03.07

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