Recombinant Newcastle disease virus expressing human IFN-λ1 (rL-hIFN-λ1) inhibits lung cancer migration through repolarizating macrophage from M2 to M1 phenotype

BACKGROUND: Tumor-associated macrophages (TAMs) are frequently infiltrated in tumor microenvironment and promote tumor progression. Lung cancer development largely depends upon the essential contributions from the TAMs which generally polarize into M2 TAMs and produce abundant anti-inflammatory fact...

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Detalles Bibliográficos
Autores principales: Yan, Yulan, Zhang, Riting, Zhang, Yao, Zhang, Xuanfeng, Zhang, Anwei, Bu, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798182/
https://www.ncbi.nlm.nih.gov/pubmed/35117705
http://dx.doi.org/10.21037/tcr-19-2320

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