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Rectal clear cell sarcoma-a case report

Gastrointestinal clear cell sarcomas (GICCSs) are malignant mesenchymal tumour that occur in the wall of gastrointestinal tract, mostly in the ileum and rarely in the rectum. These tumours are highly invasive, and often have metastasized via the lymphatic system or bloodstream by the time of diagnos...

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Autores principales: Bai, Chenguang, Dong, Min, Shen, Wenrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798232/
https://www.ncbi.nlm.nih.gov/pubmed/35117261
http://dx.doi.org/10.21037/tcr-20-1771
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author Bai, Chenguang
Dong, Min
Shen, Wenrong
author_facet Bai, Chenguang
Dong, Min
Shen, Wenrong
author_sort Bai, Chenguang
collection PubMed
description Gastrointestinal clear cell sarcomas (GICCSs) are malignant mesenchymal tumour that occur in the wall of gastrointestinal tract, mostly in the ileum and rarely in the rectum. These tumours are highly invasive, and often have metastasized via the lymphatic system or bloodstream by the time of diagnosis. In this case, the patient was admitted for gastric fundus mass, who was subsequently found and confirmed by biopsy as clear cell sarcoma of rectum. Computed tomography (CT) and magnetic resonance imaging (MRI) showed multiple metastatic lesions in lymph node, lung, liver and bone. Furthermore, energy spectrum CT was used to confirm that the nature of gastric fundus mass and rectal lesion were consistent. So, this case may be multiple clear cell sarcomas in the rectum and stomach or clear cell sarcoma in the rectum with gastric fundus metastasis. Unfortunately, after several days of immunotherapy, the patient died due to abnormal liver function. At present, GICCS mainly relies on surgical resection, and the effect of radiotherapy and chemotherapy is not good. Therefore, how to find lesions as earlier as possible and make accurate diagnosis is particularly important. CT and MRI are essential examinations in the diagnosis of tumors. Whether they are helpful for the diagnosis of GICCS is the focus of our attention.
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spelling pubmed-87982322022-02-02 Rectal clear cell sarcoma-a case report Bai, Chenguang Dong, Min Shen, Wenrong Transl Cancer Res Case Report Gastrointestinal clear cell sarcomas (GICCSs) are malignant mesenchymal tumour that occur in the wall of gastrointestinal tract, mostly in the ileum and rarely in the rectum. These tumours are highly invasive, and often have metastasized via the lymphatic system or bloodstream by the time of diagnosis. In this case, the patient was admitted for gastric fundus mass, who was subsequently found and confirmed by biopsy as clear cell sarcoma of rectum. Computed tomography (CT) and magnetic resonance imaging (MRI) showed multiple metastatic lesions in lymph node, lung, liver and bone. Furthermore, energy spectrum CT was used to confirm that the nature of gastric fundus mass and rectal lesion were consistent. So, this case may be multiple clear cell sarcomas in the rectum and stomach or clear cell sarcoma in the rectum with gastric fundus metastasis. Unfortunately, after several days of immunotherapy, the patient died due to abnormal liver function. At present, GICCS mainly relies on surgical resection, and the effect of radiotherapy and chemotherapy is not good. Therefore, how to find lesions as earlier as possible and make accurate diagnosis is particularly important. CT and MRI are essential examinations in the diagnosis of tumors. Whether they are helpful for the diagnosis of GICCS is the focus of our attention. AME Publishing Company 2020-10 /pmc/articles/PMC8798232/ /pubmed/35117261 http://dx.doi.org/10.21037/tcr-20-1771 Text en 2020 Translational Cancer Research. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.
spellingShingle Case Report
Bai, Chenguang
Dong, Min
Shen, Wenrong
Rectal clear cell sarcoma-a case report
title Rectal clear cell sarcoma-a case report
title_full Rectal clear cell sarcoma-a case report
title_fullStr Rectal clear cell sarcoma-a case report
title_full_unstemmed Rectal clear cell sarcoma-a case report
title_short Rectal clear cell sarcoma-a case report
title_sort rectal clear cell sarcoma-a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798232/
https://www.ncbi.nlm.nih.gov/pubmed/35117261
http://dx.doi.org/10.21037/tcr-20-1771
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