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Nav1.5-E3 antibody inhibits cancer progression

BACKGROUND: Nav1.5, an isoform of voltage-gated sodium channel alpha subunits, has been found to be over-expressed in cancer cells and linked to disease progression. Nav1.5-third extracellular region antibody (E3Ab) specifically targets the E3 of Nav1.5 and can lead to a subtype-specific inhibition...

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Detalles Bibliográficos
Autores principales:	Gao, Rui, Cao, Ting, Chen, Hui, Cai, Jing, Lei, Ming, Wang, Zehua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798249/ https://www.ncbi.nlm.nih.gov/pubmed/35116732 http://dx.doi.org/10.21037/tcr.2018.12.23

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