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Genetic variations of rs6928 and rs5999521 of ERK2 were found to have correlation with the risk of brain metastasis in patients with lung adenocarcinoma

BACKGROUND: Patients with lung adenocarcinoma with epidermal growth factor receptor (EGFR) mutations have a high risk of brain metastasis (BM). Mitogen-activated protein kinase (MAPK) is an important mediator of EGFR/c-MET crosstalk, which is involved in development of BM in non-small cell lung canc...

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Detalles Bibliográficos
Autores principales:	Li, Bo, Lv, Zheng, Zhao, Gang, Li, Youqi, Qiu, Xiaoguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798312/ https://www.ncbi.nlm.nih.gov/pubmed/35116533 http://dx.doi.org/10.21037/tcr-20-3069

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