The FUT2 Variant c.461G>A (p.Trp154*) Is Associated With Differentially Expressed Genes and Nasopharyngeal Microbiota Shifts in Patients With Otitis Media

Otitis media (OM) is a leading cause of childhood hearing loss. Variants in FUT2, which encodes alpha-(1,2)-fucosyltransferase, were identified to increase susceptibility to OM, potentially through shifts in the middle ear (ME) or nasopharyngeal (NP) microbiotas as mediated by transcriptional change...

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Detalles Bibliográficos
Autores principales: Elling, Christina L., Scholes, Melissa A., Streubel, Sven-Olrik, Larson, Eric D., Wine, Todd M., Bootpetch, Tori C., Yoon, Patricia J., Kofonow, Jennifer M., Gubbels, Samuel P., Cass, Stephen P., Robertson, Charles E., Jenkins, Herman A., Prager, Jeremy D., Frank, Daniel N., Chan, Kenny H., Friedman, Norman R., Ryan, Allen F., Santos-Cortez, Regie Lyn P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798324/
https://www.ncbi.nlm.nih.gov/pubmed/35096646
http://dx.doi.org/10.3389/fcimb.2021.798246

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