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Non-target genetic manipulation induces rhabdomyosarcoma in KrasPten-driven mouse model of ovarian cancer

BACKGROUND: Genetically engineered mice are ideal models to advance our understanding the tumorigenesis of ovarian cancer. Our original objective was to establish an ovarian cancer model induced by Kras activation and Pten deletion. However, proficiently establishing the model remains a technical pr...

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Detalles Bibliográficos
Autores principales:	Lai, Huiling, Guo, Yunyun, He, Weipeng, Sun, Tingting, Ouyang, Linglong, Tian, Liming, Li, Yuanyuan, Li, Xiaohui, You, Zeshan, Yang, Guofen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798327/ https://www.ncbi.nlm.nih.gov/pubmed/35117346 http://dx.doi.org/10.21037/tcr-20-2561

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