5-FU blocks shuttling of HuR mediated by PKCδ in gastric cancer cells

BACKGROUND: 5-fluorouracil (5-FU) is a common chemotherapy drug for gastric cancer. Human antigen R (HuR) is an RNA-binding protein that is also known as ELAV like RNA binding protein 1 (ELAVL1) regulates gene expression by binding to target genes 3' UTR region and is highly expressed in tumor...

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Detalles Bibliográficos
Autores principales: Wu, Wenzhi, Xu, Shengnan, Guan, Kaiyu, Zhang, Weiwei, Chen, Congde, Chen, Xiaoming, Hong, Zipu, Hua, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798337/
https://www.ncbi.nlm.nih.gov/pubmed/35117842
http://dx.doi.org/10.21037/tcr-20-2129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798337/
https://www.ncbi.nlm.nih.gov/pubmed/35117842
http://dx.doi.org/10.21037/tcr-20-2129

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