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The regulatory role of aberrant methylation of microRNA-34a promoter CpGs in osteosarcoma

BACKGROUND: The methylation of microRNAs (miRNAs) and DNA play an important role in the development of tumors. MiRNA-34a can inhibit the proliferation and metastasis of osteosarcoma cells. It was approved in a variety of tumors studies that abnormal promoter methylation leads to the reduction of miR...

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Detalles Bibliográficos
Autores principales: Shi, Jiandang, Zhao, Chen, Liu, Xuejiao, Zhang, Bing, Wang, Peng, Yang, Zongqiang, Niu, Ningkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798479/
https://www.ncbi.nlm.nih.gov/pubmed/35116985
http://dx.doi.org/10.21037/tcr.2019.09.47