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N(6)-methyladenosine could indirectly modulate translation in human cancer cells via cis-elements

BACKGROUND: N(6)-methyladenosine (m(6)A) is one of the common forms of RNA modifications. METTL3 is the essential factor that has methyltransferase activity. One important role of m6A is to regulate translation of mRNAs via reader YTHDF1. However, whether m(6)A could indirectly affect the translatio...

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Detalles Bibliográficos
Autores principales: Zhang, Yongchun, Chen, Zhiying, Zhang, Lijian, Jiang, Peng, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798532/
https://www.ncbi.nlm.nih.gov/pubmed/35116942
http://dx.doi.org/10.21037/tcr.2019.09.18

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