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Downregulation of hexokinase 2 improves radiosensitivity of breast cancer

BACKGROUND: Hexokinase 2 (HK2) is a major glycolytic enzyme that plays a critical role in the development of tumor metabolism. Triple negative breast cancers (TNBC) have high glycolytic activity and poor prognosis. This study explored the effect of HK2 on radiotherapy (RT) sensitivity of TNBC. METHO...

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Detalles Bibliográficos
Autores principales: Zhang, Dan, Wang, Hui, Yu, Wenjing, Qiao, Feng, Su, Xiaoyu, Xu, Huiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798562/
https://www.ncbi.nlm.nih.gov/pubmed/35116758
http://dx.doi.org/10.21037/tcr.2019.01.37