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Downregulation of hexokinase 2 improves radiosensitivity of breast cancer
BACKGROUND: Hexokinase 2 (HK2) is a major glycolytic enzyme that plays a critical role in the development of tumor metabolism. Triple negative breast cancers (TNBC) have high glycolytic activity and poor prognosis. This study explored the effect of HK2 on radiotherapy (RT) sensitivity of TNBC. METHO...
Autores principales: | Zhang, Dan, Wang, Hui, Yu, Wenjing, Qiao, Feng, Su, Xiaoyu, Xu, Huiqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798562/ https://www.ncbi.nlm.nih.gov/pubmed/35116758 http://dx.doi.org/10.21037/tcr.2019.01.37 |
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