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Novel Clinical Monitoring Approaches for Reemergence of Diphtheria Myocarditis, Vietnam

Diphtheria is a life-threatening, vaccine-preventable disease caused by toxigenic Corynebacterium bacterial species that continues to cause substantial disease and death worldwide, particularly in vulnerable populations. Further outbreaks of vaccine-preventable diseases are forecast because of healt...

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Autores principales: Chanh, Ho Quang, Trieu, Huynh Trung, Vuong, Huynh Ngoc Thien, Hung, Tran Kim, Phan, Tu Qui, Campbell, James, Pley, Caitlin, Yacoub, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798685/
https://www.ncbi.nlm.nih.gov/pubmed/35075995
http://dx.doi.org/10.3201/eid2802.210555
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author Chanh, Ho Quang
Trieu, Huynh Trung
Vuong, Huynh Ngoc Thien
Hung, Tran Kim
Phan, Tu Qui
Campbell, James
Pley, Caitlin
Yacoub, Sophie
author_facet Chanh, Ho Quang
Trieu, Huynh Trung
Vuong, Huynh Ngoc Thien
Hung, Tran Kim
Phan, Tu Qui
Campbell, James
Pley, Caitlin
Yacoub, Sophie
author_sort Chanh, Ho Quang
collection PubMed
description Diphtheria is a life-threatening, vaccine-preventable disease caused by toxigenic Corynebacterium bacterial species that continues to cause substantial disease and death worldwide, particularly in vulnerable populations. Further outbreaks of vaccine-preventable diseases are forecast because of health service disruptions caused by the coronavirus disease pandemic. Diphtheria causes a spectrum of clinical disease, ranging from cutaneous forms to severe respiratory infections with systemic complications, including cardiac and neurologic. In this synopsis, we describe a case of oropharyngeal diphtheria in a 7-year-old boy in Vietnam who experienced severe myocarditis complications. We also review the cardiac complications of diphtheria and discuss how noninvasive bedside imaging technologies to monitor myocardial function and hemodynamic parameters can help improve the management of this neglected infectious disease.
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spelling pubmed-87986852022-02-08 Novel Clinical Monitoring Approaches for Reemergence of Diphtheria Myocarditis, Vietnam Chanh, Ho Quang Trieu, Huynh Trung Vuong, Huynh Ngoc Thien Hung, Tran Kim Phan, Tu Qui Campbell, James Pley, Caitlin Yacoub, Sophie Emerg Infect Dis Synopsis Diphtheria is a life-threatening, vaccine-preventable disease caused by toxigenic Corynebacterium bacterial species that continues to cause substantial disease and death worldwide, particularly in vulnerable populations. Further outbreaks of vaccine-preventable diseases are forecast because of health service disruptions caused by the coronavirus disease pandemic. Diphtheria causes a spectrum of clinical disease, ranging from cutaneous forms to severe respiratory infections with systemic complications, including cardiac and neurologic. In this synopsis, we describe a case of oropharyngeal diphtheria in a 7-year-old boy in Vietnam who experienced severe myocarditis complications. We also review the cardiac complications of diphtheria and discuss how noninvasive bedside imaging technologies to monitor myocardial function and hemodynamic parameters can help improve the management of this neglected infectious disease. Centers for Disease Control and Prevention 2022-02 /pmc/articles/PMC8798685/ /pubmed/35075995 http://dx.doi.org/10.3201/eid2802.210555 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Synopsis
Chanh, Ho Quang
Trieu, Huynh Trung
Vuong, Huynh Ngoc Thien
Hung, Tran Kim
Phan, Tu Qui
Campbell, James
Pley, Caitlin
Yacoub, Sophie
Novel Clinical Monitoring Approaches for Reemergence of Diphtheria Myocarditis, Vietnam
title Novel Clinical Monitoring Approaches for Reemergence of Diphtheria Myocarditis, Vietnam
title_full Novel Clinical Monitoring Approaches for Reemergence of Diphtheria Myocarditis, Vietnam
title_fullStr Novel Clinical Monitoring Approaches for Reemergence of Diphtheria Myocarditis, Vietnam
title_full_unstemmed Novel Clinical Monitoring Approaches for Reemergence of Diphtheria Myocarditis, Vietnam
title_short Novel Clinical Monitoring Approaches for Reemergence of Diphtheria Myocarditis, Vietnam
title_sort novel clinical monitoring approaches for reemergence of diphtheria myocarditis, vietnam
topic Synopsis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798685/
https://www.ncbi.nlm.nih.gov/pubmed/35075995
http://dx.doi.org/10.3201/eid2802.210555
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