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Atorvastatin inhibits pancreatic cancer cells proliferation and invasion likely by suppressing neurotrophin receptor signaling

BACKGROUND: Pancreatic cancer (PC) is aggressive and with poor clinical prognosis. However, mechanisms underlying the aggressiveness of PC remain unclear. Increasing evidence indicates that cholesterol, a major source of bio-energy, is required for the progression of human cancers including PC. Ther...

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Detalles Bibliográficos
Autores principales: Cai, Shang, Chen, Qingqing, Xu, Yingying, Zhuang, Qianfeng, Ji, Shengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798715/
https://www.ncbi.nlm.nih.gov/pubmed/35117491
http://dx.doi.org/10.21037/tcr.2020.01.27