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Analysis of novel enzalutamide-resistant cells: upregulation of testis-specific Y-encoded protein gene promotes the expression of androgen receptor splicing variant 7

BACKGROUND: Enzalutamide, a second-generation antiandrogen, is an approved medicine for the treatment of metastatic castration-resistant prostate cancer (CRPC); however, the mechanisms behind the resistance are not completely understood. In the present study, we established enzalutamide-resistant ce...

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Detalles Bibliográficos
Autores principales: Seki, Masanao, Kajiwara, Daisuke, Mizutani, Hiroya, Minamiguchi, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798816/
https://www.ncbi.nlm.nih.gov/pubmed/35117234
http://dx.doi.org/10.21037/tcr-20-1463