Cargando…

Glutaminase 2 functions as a tumor suppressor gene in gastric cancer

BACKGROUND: Glutaminase 2 (GLS2) has been described as a tumor suppressor in hepatocellular carcinoma (HCC) and colon cancer. This study aimed to investigate the expression of GLS2 and its biological role in gastric cancer. METHODS: The expression of GLS2 was determined by quantitative Real-time PCR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Liang, Zhou, Dong, Li, Fang, Ji, Lijiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798858/ https://www.ncbi.nlm.nih.gov/pubmed/35117852 http://dx.doi.org/10.21037/tcr-20-2246

Ejemplares similares

Tumor-suppressive function of EZH2 is through inhibiting glutaminase
por: Liu, Yongfeng, et al.
Publicado: (2021)

Q-ing tumor glutaminase therapy
por: Stine, Zachary E., et al.
Publicado: (2015)

Upregulation of the Glutaminase II Pathway Contributes to Glutamate Production upon Glutaminase 1 Inhibition in Pancreatic Cancer
por: Udupa, Sunag, et al.
Publicado: (2019)

RAI2 acts as a tumor suppressor with functional significance in gastric cancer
por: Lou, Xiaoli, et al.
Publicado: (2023)

Pyruvate kinase isozyme M2 and glutaminase might be promising molecular targets for the treatment of gastric cancer
por: Kitayama, Kishu, et al.
Publicado: (2017)

Governing glutaminolysis by regulation of glutaminase succinylation
por: Ma, Qingxia, et al.
Publicado: (2021)

Targeting glutaminase and mTOR
por: Tanaka, Kazuhiro, et al.
Publicado: (2015)

Epigenetic silencing of glutaminase 2 in human liver and colon cancers
por: Zhang, Jianbin, et al.
Publicado: (2013)

Comparison of glutaminase and cancer antigen 125 for distinguishing benign and malignant ovarian tumors
por: Winarno, Gatot Nyarumenteng Adhipurnawan, et al.
Publicado: (2023)

Metabolic modulation of neurogenesis: Role of glutaminase-2
por: Salomoni, Paolo
Publicado: (2014)

TFEB Supports Pancreatic Cancer Growth through the Transcriptional Regulation of Glutaminase
por: Kim, Ji Hye, et al.
Publicado: (2021)

Loss of mammalian glutaminase orthologs impairs sperm function in Caenorhabditis elegans
por: Liang, Qifei, et al.
Publicado: (2023)

The Role of Glutamine and Glutaminase in Pulmonary Hypertension
por: Wang, Shang, et al.
Publicado: (2022)

The Function of circRNA-0047604 in Regulating the Tumor Suppressor Gene DACH1 in Breast Cancer
por: Zhao, Bingkun, et al.
Publicado: (2022)

MiRNA-4537 functions as a tumor suppressor in gastric cancer and increases the radiosensitivity of gastric cancer cells
por: Liu, Jia, et al.
Publicado: (2021)

MicroRNA-219-2-3p Functions as a Tumor Suppressor in Gastric Cancer and Is Regulated by DNA Methylation
por: Lei, Huizi, et al.
Publicado: (2013)

Dendrimer-conjugated glutaminase inhibitor selectively targets microglial glutaminase in a mouse model of Rett syndrome
por: Khoury, Elizabeth Smith, et al.
Publicado: (2020)

The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy
por: Lukey, Michael J., et al.
Publicado: (2016)

Recent progress in the study of methylated tumor suppressor genes in gastric cancer
por: Hu, Xiao-Tong, et al.
Publicado: (2013)

Galanin is an epigenetically silenced tumor suppressor gene in gastric cancer cells
por: Yoon, Daseul, et al.
Publicado: (2018)

HOXA5 is a tumor suppressor gene that is decreased in gastric cancer
por: Peng, Xudong, et al.
Publicado: (2018)

FLRT2 functions as Tumor Suppressor gene inactivated by promoter methylation in Colorectal Cancer
por: Guo, Xiaohong, et al.
Publicado: (2020)

Effect of glutaminase inhibition on cancer-induced bone pain
por: Fazzari, Jennifer, et al.
Publicado: (2019)

The Biological and Clinical Significance of Glutaminase in Luminal Breast Cancer
por: Masisi, Brendah K., et al.
Publicado: (2021)

Aberrant expression of the candidate tumor suppressor gene DAL-1 due to hypermethylation in gastric cancer
por: Wang, Hao, et al.
Publicado: (2016)

Targeting glutaminase to starve lymphoma cells
por: Dumontet, Charles
Publicado: (2022)

Function and mechanism of tumor suppressor gene LRRC4/NGL-2
por: Li, Peiyao, et al.
Publicado: (2014)

miR-429 functions as a tumor suppressor by targeting FSCN1 in gastric cancer cells
por: Zhang, Min, et al.
Publicado: (2016)

MiR-638 acts as a tumor suppressor gene in gastric cancer
por: Shen, Yu, et al.
Publicado: (2017)

Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer
por: Kang, Myoung-Hee, et al.
Publicado: (2018)

Glutaminase 1 expression in colorectal cancer cells is induced by hypoxia and required for tumor growth, invasion, and metastatic colonization
por: Xiang, Lisha, et al.
Publicado: (2019)

Glutaminase: A Hot Spot For Regulation Of Cancer Cell Metabolism?
por: Erickson, Jon W., et al.
Publicado: (2010)

Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis
por: Wang, Tao, et al.
Publicado: (2022)

CircLMTK2 acts as a novel tumor suppressor in gastric cancer
por: He, Jian, et al.
Publicado: (2019)

Self-Assembled Micellar Glutaminase Allosteric Inhibitor for Effective Therapeutic Intervention
por: Fang, Jinzhang, et al.
Publicado: (2022)

Safety assessment of glutaminase from Aspergillus niger
por: Vo, Trung Duc, et al.
Publicado: (2020)

Targeting hepatic glutaminase activity to ameliorate hyperglycemia
por: Miller, Russell A., et al.
Publicado: (2018)

Glutaminase inhibition in renal cell carcinoma therapy
por: Raczka, Aleksandra M., et al.
Publicado: (2019)

Identification and characterization of a novel glutaminase inhibitor
por: Cederkvist, Henning, et al.
Publicado: (2021)

Clinicopathological Significance of Large Tumor Suppressor (LATS) Expression in Gastric Cancer
por: Son, Myoung Won, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_t9lf0rke0m9htccmjcd7cmn2p7