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Tracheoesophageal fistula caused by chemotherapy in primary thyroid lymphoma: a case report
Primary thyroid lymphoma (PTL) is a rare malignant tumor of the thyroid, the diagnosis, and treatment of which are still controversial. Although the treatment of thyroid lymphoma causing respiratory obstruction is controversial, chemotherapy is considered the most effective treatment. Tracheoesophag...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798900/ https://www.ncbi.nlm.nih.gov/pubmed/35116661 http://dx.doi.org/10.21037/tcr-21-486 |
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author | Wang, Chun Li, Zhirong Tian, Wuguo |
author_facet | Wang, Chun Li, Zhirong Tian, Wuguo |
author_sort | Wang, Chun |
collection | PubMed |
description | Primary thyroid lymphoma (PTL) is a rare malignant tumor of the thyroid, the diagnosis, and treatment of which are still controversial. Although the treatment of thyroid lymphoma causing respiratory obstruction is controversial, chemotherapy is considered the most effective treatment. Tracheoesophageal fistula is an extremely rare complication of chemotherapy. Here, we report a case of respiratory obstruction caused by a thyroid tumor. A 66-year-old female patient visited the hospital with a goiter with dyspnea. The patient was diagnosed with diffuse large B-cell lymphoma of the thyroid by core needle biopsy. After chemotherapy with a cyclophosphamide vincristine prednisone (CVP) regimen, the tumor obviously subsided, but the patient began to experience clinical symptoms such as hoarseness and difficulty drinking. Fiberoptic bronchoscopy and neck computed tomography revealed a tracheoesophageal fistula. The phenomenon of tracheoesophageal fistula resulting from chemotherapy for thyroid lymphoma is extremely rare. Standard treatment for thyroid lymphoma that causes respiratory tract obstruction does not exist. Through clinical case sharing, increase awareness and early recognition are particularly important in order to minimize appropriately the effect of the event and through this case report, so as to provide some suggestions for clinicians. Cases of airway obstruction should be fully evaluated before treatment, and temporary airway protection measures, such as tracheotomy, surgical decompression, and tracheal metal. |
format | Online Article Text |
id | pubmed-8798900 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-87989002022-02-02 Tracheoesophageal fistula caused by chemotherapy in primary thyroid lymphoma: a case report Wang, Chun Li, Zhirong Tian, Wuguo Transl Cancer Res Case Report Primary thyroid lymphoma (PTL) is a rare malignant tumor of the thyroid, the diagnosis, and treatment of which are still controversial. Although the treatment of thyroid lymphoma causing respiratory obstruction is controversial, chemotherapy is considered the most effective treatment. Tracheoesophageal fistula is an extremely rare complication of chemotherapy. Here, we report a case of respiratory obstruction caused by a thyroid tumor. A 66-year-old female patient visited the hospital with a goiter with dyspnea. The patient was diagnosed with diffuse large B-cell lymphoma of the thyroid by core needle biopsy. After chemotherapy with a cyclophosphamide vincristine prednisone (CVP) regimen, the tumor obviously subsided, but the patient began to experience clinical symptoms such as hoarseness and difficulty drinking. Fiberoptic bronchoscopy and neck computed tomography revealed a tracheoesophageal fistula. The phenomenon of tracheoesophageal fistula resulting from chemotherapy for thyroid lymphoma is extremely rare. Standard treatment for thyroid lymphoma that causes respiratory tract obstruction does not exist. Through clinical case sharing, increase awareness and early recognition are particularly important in order to minimize appropriately the effect of the event and through this case report, so as to provide some suggestions for clinicians. Cases of airway obstruction should be fully evaluated before treatment, and temporary airway protection measures, such as tracheotomy, surgical decompression, and tracheal metal. AME Publishing Company 2021-07 /pmc/articles/PMC8798900/ /pubmed/35116661 http://dx.doi.org/10.21037/tcr-21-486 Text en 2021 Translational Cancer Research. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/. |
spellingShingle | Case Report Wang, Chun Li, Zhirong Tian, Wuguo Tracheoesophageal fistula caused by chemotherapy in primary thyroid lymphoma: a case report |
title | Tracheoesophageal fistula caused by chemotherapy in primary thyroid lymphoma: a case report |
title_full | Tracheoesophageal fistula caused by chemotherapy in primary thyroid lymphoma: a case report |
title_fullStr | Tracheoesophageal fistula caused by chemotherapy in primary thyroid lymphoma: a case report |
title_full_unstemmed | Tracheoesophageal fistula caused by chemotherapy in primary thyroid lymphoma: a case report |
title_short | Tracheoesophageal fistula caused by chemotherapy in primary thyroid lymphoma: a case report |
title_sort | tracheoesophageal fistula caused by chemotherapy in primary thyroid lymphoma: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798900/ https://www.ncbi.nlm.nih.gov/pubmed/35116661 http://dx.doi.org/10.21037/tcr-21-486 |
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