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Genome-wide expression changes mediated by A-to-I RNA editing correlate with hepatic oncogenesis

BACKGROUND: Adenosine-to-inosine (A-to-I) RNA editing is one of the most prevalent RNA modifications in the animal kingdom. Since inosine is recognized as guanosines, the A-to-I process mimics A-to-G DNA mutations but can be controlled in a more flexible manner compared to DNA alterations. METHODS:...

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Detalles Bibliográficos
Autores principales: Li, Jian, Li, Qun, Yu, Chun-Peng, Chang, Shuai, Xie, Ling-Ling, Wang, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798912/
https://www.ncbi.nlm.nih.gov/pubmed/35116583
http://dx.doi.org/10.21037/tcr-21-236