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Ultrasound-guided secondary radiofrequency ablation combined with chemotherapy in gastric cancer with recurrent liver metastasis

BACKGROUND: The incidence and mortality of gastric cancer are in the second and third place of malignant tumor in China, respectively. Liver metastasis is an important cause of death of these patients. This study is to explore whether the secondary radiofrequency ablation (RFA) treatment can prolong...

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Autores principales: Fan, Xiaoxiang, Zhang, Yan, Zhang, Meiwu, Mao, Dafeng, Jiang, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798951/
https://www.ncbi.nlm.nih.gov/pubmed/35117595
http://dx.doi.org/10.21037/tcr.2020.03.45
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author Fan, Xiaoxiang
Zhang, Yan
Zhang, Meiwu
Mao, Dafeng
Jiang, Haitao
author_facet Fan, Xiaoxiang
Zhang, Yan
Zhang, Meiwu
Mao, Dafeng
Jiang, Haitao
author_sort Fan, Xiaoxiang
collection PubMed
description BACKGROUND: The incidence and mortality of gastric cancer are in the second and third place of malignant tumor in China, respectively. Liver metastasis is an important cause of death of these patients. This study is to explore whether the secondary radiofrequency ablation (RFA) treatment can prolong the survival period and improve the life quality of patients with gastric cancer and recurrent liver metastases. METHODS: A total of 87 patients with gastric cancer and recurrent liver metastases were retrospective analyzed, 46 cases were assigned into study group and 41 cases in control group. The efficacy of the two groups was observed, and the prognostic factors were analyzed. RESULTS: The median survival time in the study group was significantly longer than that in the control group (P<0.05). The survival rate of the study group was significantly higher than that of the control group (both P<0.05). The life quality scores of the study group were significantly higher than the control group (both P<0.05). CONCLUSIONS: Ultrasound-mediated secondary RFA combined with chemotherapy is superior to chemotherapy alone in the treatment of gastric cancer with recurrent liver metastases.
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spelling pubmed-87989512022-02-02 Ultrasound-guided secondary radiofrequency ablation combined with chemotherapy in gastric cancer with recurrent liver metastasis Fan, Xiaoxiang Zhang, Yan Zhang, Meiwu Mao, Dafeng Jiang, Haitao Transl Cancer Res Original Article BACKGROUND: The incidence and mortality of gastric cancer are in the second and third place of malignant tumor in China, respectively. Liver metastasis is an important cause of death of these patients. This study is to explore whether the secondary radiofrequency ablation (RFA) treatment can prolong the survival period and improve the life quality of patients with gastric cancer and recurrent liver metastases. METHODS: A total of 87 patients with gastric cancer and recurrent liver metastases were retrospective analyzed, 46 cases were assigned into study group and 41 cases in control group. The efficacy of the two groups was observed, and the prognostic factors were analyzed. RESULTS: The median survival time in the study group was significantly longer than that in the control group (P<0.05). The survival rate of the study group was significantly higher than that of the control group (both P<0.05). The life quality scores of the study group were significantly higher than the control group (both P<0.05). CONCLUSIONS: Ultrasound-mediated secondary RFA combined with chemotherapy is superior to chemotherapy alone in the treatment of gastric cancer with recurrent liver metastases. AME Publishing Company 2020-04 /pmc/articles/PMC8798951/ /pubmed/35117595 http://dx.doi.org/10.21037/tcr.2020.03.45 Text en 2020 Translational Cancer Research. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.
spellingShingle Original Article
Fan, Xiaoxiang
Zhang, Yan
Zhang, Meiwu
Mao, Dafeng
Jiang, Haitao
Ultrasound-guided secondary radiofrequency ablation combined with chemotherapy in gastric cancer with recurrent liver metastasis
title Ultrasound-guided secondary radiofrequency ablation combined with chemotherapy in gastric cancer with recurrent liver metastasis
title_full Ultrasound-guided secondary radiofrequency ablation combined with chemotherapy in gastric cancer with recurrent liver metastasis
title_fullStr Ultrasound-guided secondary radiofrequency ablation combined with chemotherapy in gastric cancer with recurrent liver metastasis
title_full_unstemmed Ultrasound-guided secondary radiofrequency ablation combined with chemotherapy in gastric cancer with recurrent liver metastasis
title_short Ultrasound-guided secondary radiofrequency ablation combined with chemotherapy in gastric cancer with recurrent liver metastasis
title_sort ultrasound-guided secondary radiofrequency ablation combined with chemotherapy in gastric cancer with recurrent liver metastasis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798951/
https://www.ncbi.nlm.nih.gov/pubmed/35117595
http://dx.doi.org/10.21037/tcr.2020.03.45
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AT maodafeng ultrasoundguidedsecondaryradiofrequencyablationcombinedwithchemotherapyingastriccancerwithrecurrentlivermetastasis
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