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IL-1β secreted by macrophage M2 promotes metastasis of osteosarcoma via NF-κB/miR-181α-5p/RASSF1A/Wnt pathway

BACKGROUND: Ras-associated domain family protein1 isoform A (RASSF1A) was significantly absent in clinical samples and many osteosarcoma (OS) cell lines. Overexpression of RASSF1A could suppress OS metastasis, which may be mediated by tumor-associated macrophages polarized M2 (M2-TAMs). However, the...

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Detalles Bibliográficos
Autores principales:	Han, Zhi-Peng, Liu, Dong-Biao, Wu, Liu-Qing, Li, Qin, Wang, Zheng-Guang, Zang, Xiao-Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8798966/ https://www.ncbi.nlm.nih.gov/pubmed/35117631 http://dx.doi.org/10.21037/tcr.2020.02.52

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