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The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review

Pancreatic cancer is one of the worst prognoses of all malignant tumors, with an annual incidence near its annual mortality rate. To improve the prognosis of patients with pancreatic cancer, it is essential to diagnose and evaluate pancreatic cancer early. Imaging examinations play an essential role...

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Autores principales: Pu, Yongzhu, Wang, Chun, Zhao, Sheng, Xie, Ran, Zhao, Lei, Li, Kun, Yang, Conghui, Zhang, Rui, Tian, Yadong, Tan, Lixian, Li, Jindan, Li, Shujuan, Chen, Long, Sun, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799156/
https://www.ncbi.nlm.nih.gov/pubmed/35116659
http://dx.doi.org/10.21037/tcr-21-169
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author Pu, Yongzhu
Wang, Chun
Zhao, Sheng
Xie, Ran
Zhao, Lei
Li, Kun
Yang, Conghui
Zhang, Rui
Tian, Yadong
Tan, Lixian
Li, Jindan
Li, Shujuan
Chen, Long
Sun, Hua
author_facet Pu, Yongzhu
Wang, Chun
Zhao, Sheng
Xie, Ran
Zhao, Lei
Li, Kun
Yang, Conghui
Zhang, Rui
Tian, Yadong
Tan, Lixian
Li, Jindan
Li, Shujuan
Chen, Long
Sun, Hua
author_sort Pu, Yongzhu
collection PubMed
description Pancreatic cancer is one of the worst prognoses of all malignant tumors, with an annual incidence near its annual mortality rate. To improve the prognosis of patients with pancreatic cancer, it is essential to diagnose and evaluate pancreatic cancer early. Imaging examinations play an essential role in tumor detection, staging, and surgical resection assessment and can provide reliable evidence for the diagnosis and treatment of pancreatic cancer. Currently, imaging techniques commonly used for pancreatic cancer include endoscopic ultrasound (EUS), conventional ultrasound, magnetic resonance imaging (MRI), multidetector spiral computed tomography (MDCT), positron emission tomography/computed tomography (PET/CT), and others PET/CT is a new imaging device composed of PET and CT. (18)F-Fluorodeoxyglucose ((18)F-FDG) is a commonly used tracer in the clinic. Cancer cells are more robust than other ordinary cells in that they can ingest glucose, and the structure of glucose is similar to the structure of (18)F-FDG. Therefore, after the injection of (18)F-FDG, (18)F-FDG in tumor cells appears very thick during PET scanning. Therefore, PET/CT can determine the metabolic capacity and anatomical position of pancreatic tumor cells in the body accurately diagnose the patient's condition and tumor location. It plays a vital role in early diagnosis and accurate staging, predicts survival, and monitors therapeutic effectiveness and pancreatic cancer recurrence. Although (18)F-FDG PET/CT has limitations in identifying inflammatory diseases and tumors, it still has good development potential. This article reviews the clinical application of (18)F-FDG PET/CT in pancreatic cancer.
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spelling pubmed-87991562022-02-02 The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review Pu, Yongzhu Wang, Chun Zhao, Sheng Xie, Ran Zhao, Lei Li, Kun Yang, Conghui Zhang, Rui Tian, Yadong Tan, Lixian Li, Jindan Li, Shujuan Chen, Long Sun, Hua Transl Cancer Res Review Article Pancreatic cancer is one of the worst prognoses of all malignant tumors, with an annual incidence near its annual mortality rate. To improve the prognosis of patients with pancreatic cancer, it is essential to diagnose and evaluate pancreatic cancer early. Imaging examinations play an essential role in tumor detection, staging, and surgical resection assessment and can provide reliable evidence for the diagnosis and treatment of pancreatic cancer. Currently, imaging techniques commonly used for pancreatic cancer include endoscopic ultrasound (EUS), conventional ultrasound, magnetic resonance imaging (MRI), multidetector spiral computed tomography (MDCT), positron emission tomography/computed tomography (PET/CT), and others PET/CT is a new imaging device composed of PET and CT. (18)F-Fluorodeoxyglucose ((18)F-FDG) is a commonly used tracer in the clinic. Cancer cells are more robust than other ordinary cells in that they can ingest glucose, and the structure of glucose is similar to the structure of (18)F-FDG. Therefore, after the injection of (18)F-FDG, (18)F-FDG in tumor cells appears very thick during PET scanning. Therefore, PET/CT can determine the metabolic capacity and anatomical position of pancreatic tumor cells in the body accurately diagnose the patient's condition and tumor location. It plays a vital role in early diagnosis and accurate staging, predicts survival, and monitors therapeutic effectiveness and pancreatic cancer recurrence. Although (18)F-FDG PET/CT has limitations in identifying inflammatory diseases and tumors, it still has good development potential. This article reviews the clinical application of (18)F-FDG PET/CT in pancreatic cancer. AME Publishing Company 2021-07 /pmc/articles/PMC8799156/ /pubmed/35116659 http://dx.doi.org/10.21037/tcr-21-169 Text en 2021 Translational Cancer Research. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.
spellingShingle Review Article
Pu, Yongzhu
Wang, Chun
Zhao, Sheng
Xie, Ran
Zhao, Lei
Li, Kun
Yang, Conghui
Zhang, Rui
Tian, Yadong
Tan, Lixian
Li, Jindan
Li, Shujuan
Chen, Long
Sun, Hua
The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review
title The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review
title_full The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review
title_fullStr The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review
title_full_unstemmed The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review
title_short The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review
title_sort clinical application of (18)f-fdg pet/ct in pancreatic cancer: a narrative review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799156/
https://www.ncbi.nlm.nih.gov/pubmed/35116659
http://dx.doi.org/10.21037/tcr-21-169
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