Cargando…
The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review
Pancreatic cancer is one of the worst prognoses of all malignant tumors, with an annual incidence near its annual mortality rate. To improve the prognosis of patients with pancreatic cancer, it is essential to diagnose and evaluate pancreatic cancer early. Imaging examinations play an essential role...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799156/ https://www.ncbi.nlm.nih.gov/pubmed/35116659 http://dx.doi.org/10.21037/tcr-21-169 |
_version_ | 1784642000331472896 |
---|---|
author | Pu, Yongzhu Wang, Chun Zhao, Sheng Xie, Ran Zhao, Lei Li, Kun Yang, Conghui Zhang, Rui Tian, Yadong Tan, Lixian Li, Jindan Li, Shujuan Chen, Long Sun, Hua |
author_facet | Pu, Yongzhu Wang, Chun Zhao, Sheng Xie, Ran Zhao, Lei Li, Kun Yang, Conghui Zhang, Rui Tian, Yadong Tan, Lixian Li, Jindan Li, Shujuan Chen, Long Sun, Hua |
author_sort | Pu, Yongzhu |
collection | PubMed |
description | Pancreatic cancer is one of the worst prognoses of all malignant tumors, with an annual incidence near its annual mortality rate. To improve the prognosis of patients with pancreatic cancer, it is essential to diagnose and evaluate pancreatic cancer early. Imaging examinations play an essential role in tumor detection, staging, and surgical resection assessment and can provide reliable evidence for the diagnosis and treatment of pancreatic cancer. Currently, imaging techniques commonly used for pancreatic cancer include endoscopic ultrasound (EUS), conventional ultrasound, magnetic resonance imaging (MRI), multidetector spiral computed tomography (MDCT), positron emission tomography/computed tomography (PET/CT), and others PET/CT is a new imaging device composed of PET and CT. (18)F-Fluorodeoxyglucose ((18)F-FDG) is a commonly used tracer in the clinic. Cancer cells are more robust than other ordinary cells in that they can ingest glucose, and the structure of glucose is similar to the structure of (18)F-FDG. Therefore, after the injection of (18)F-FDG, (18)F-FDG in tumor cells appears very thick during PET scanning. Therefore, PET/CT can determine the metabolic capacity and anatomical position of pancreatic tumor cells in the body accurately diagnose the patient's condition and tumor location. It plays a vital role in early diagnosis and accurate staging, predicts survival, and monitors therapeutic effectiveness and pancreatic cancer recurrence. Although (18)F-FDG PET/CT has limitations in identifying inflammatory diseases and tumors, it still has good development potential. This article reviews the clinical application of (18)F-FDG PET/CT in pancreatic cancer. |
format | Online Article Text |
id | pubmed-8799156 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-87991562022-02-02 The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review Pu, Yongzhu Wang, Chun Zhao, Sheng Xie, Ran Zhao, Lei Li, Kun Yang, Conghui Zhang, Rui Tian, Yadong Tan, Lixian Li, Jindan Li, Shujuan Chen, Long Sun, Hua Transl Cancer Res Review Article Pancreatic cancer is one of the worst prognoses of all malignant tumors, with an annual incidence near its annual mortality rate. To improve the prognosis of patients with pancreatic cancer, it is essential to diagnose and evaluate pancreatic cancer early. Imaging examinations play an essential role in tumor detection, staging, and surgical resection assessment and can provide reliable evidence for the diagnosis and treatment of pancreatic cancer. Currently, imaging techniques commonly used for pancreatic cancer include endoscopic ultrasound (EUS), conventional ultrasound, magnetic resonance imaging (MRI), multidetector spiral computed tomography (MDCT), positron emission tomography/computed tomography (PET/CT), and others PET/CT is a new imaging device composed of PET and CT. (18)F-Fluorodeoxyglucose ((18)F-FDG) is a commonly used tracer in the clinic. Cancer cells are more robust than other ordinary cells in that they can ingest glucose, and the structure of glucose is similar to the structure of (18)F-FDG. Therefore, after the injection of (18)F-FDG, (18)F-FDG in tumor cells appears very thick during PET scanning. Therefore, PET/CT can determine the metabolic capacity and anatomical position of pancreatic tumor cells in the body accurately diagnose the patient's condition and tumor location. It plays a vital role in early diagnosis and accurate staging, predicts survival, and monitors therapeutic effectiveness and pancreatic cancer recurrence. Although (18)F-FDG PET/CT has limitations in identifying inflammatory diseases and tumors, it still has good development potential. This article reviews the clinical application of (18)F-FDG PET/CT in pancreatic cancer. AME Publishing Company 2021-07 /pmc/articles/PMC8799156/ /pubmed/35116659 http://dx.doi.org/10.21037/tcr-21-169 Text en 2021 Translational Cancer Research. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/. |
spellingShingle | Review Article Pu, Yongzhu Wang, Chun Zhao, Sheng Xie, Ran Zhao, Lei Li, Kun Yang, Conghui Zhang, Rui Tian, Yadong Tan, Lixian Li, Jindan Li, Shujuan Chen, Long Sun, Hua The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review |
title | The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review |
title_full | The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review |
title_fullStr | The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review |
title_full_unstemmed | The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review |
title_short | The clinical application of (18)F-FDG PET/CT in pancreatic cancer: a narrative review |
title_sort | clinical application of (18)f-fdg pet/ct in pancreatic cancer: a narrative review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799156/ https://www.ncbi.nlm.nih.gov/pubmed/35116659 http://dx.doi.org/10.21037/tcr-21-169 |
work_keys_str_mv | AT puyongzhu theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT wangchun theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT zhaosheng theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT xieran theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT zhaolei theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT likun theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT yangconghui theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT zhangrui theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT tianyadong theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT tanlixian theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT lijindan theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT lishujuan theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT chenlong theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT sunhua theclinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT puyongzhu clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT wangchun clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT zhaosheng clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT xieran clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT zhaolei clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT likun clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT yangconghui clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT zhangrui clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT tianyadong clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT tanlixian clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT lijindan clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT lishujuan clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT chenlong clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview AT sunhua clinicalapplicationof18ffdgpetctinpancreaticcanceranarrativereview |