Cargando…

Role of Sex Hormones at Different Physiobiological Conditions and Therapeutic Potential in MBD2 Mediated Severe Asthma

Sex hormone has become a “hot topic” to evaluate the hormonal therapeutic potential in severe asthma. Th17 cell is one of the main influencing factors involved in the pathogenesis of severe asthma, hence also called as kernel of severe asthma, and Th17 subtype of non-T2 asthma is less responsive (re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wasti, Binaya, Chen, Zhifeng, He, Yi, Duan, Wen Tao, Liu, Shao-Kun, Xiang, Xu-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799366/ https://www.ncbi.nlm.nih.gov/pubmed/35096261 http://dx.doi.org/10.1155/2021/7097797

Ejemplares similares

MBD2 as a Potential Novel Biomarker for Identifying Severe Asthma With Different Endotypes
por: Chen, Zhifeng, et al.
Publicado: (2021)

Androgen Plays a Potential Novel Hormonal Therapeutic Role in Th17 Cells Predominant Neutrophilic Severe Asthma by Attenuating BECs Regulated Th17 Cells Differentiation via MBD2 Expression
por: Wasti, Binaya, et al.
Publicado: (2022)

miR-146a-3p as a potential novel therapeutic by targeting MBD2 to mediate Th17 differentiation in Th17 predominant neutrophilic severe asthma
por: Duan, Wentao, et al.
Publicado: (2023)

MBD2 mediates Th17 cell differentiation by regulating MINK1 in Th17-dominant asthma
por: Chen, Zhifeng, et al.
Publicado: (2022)

Role of Epigenetics in the Pathogenesis, Treatment, Prediction, and Cellular Transformation of Asthma
por: Wasti, Binaya, et al.
Publicado: (2021)

lncRNA CRNDE Affects Th17/IL-17A and Inhibits Epithelial-Mesenchymal Transition in Lung Epithelial Cells Reducing Asthma Signs
por: Yuan, Yu, et al.
Publicado: (2023)

Clinical characteristics and risk factors of patients with eosinophilic fasciitis associated with pleural effusion
por: Chen, Zhifeng, et al.
Publicado: (2023)

MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression
por: Jia, Aijun, et al.
Publicado: (2017)

Alanylglutamine Relieved Asthma Symptoms by Regulating Gut Microbiota and the Derived Metabolites in Mice
por: Liu, Shao-Kun, et al.
Publicado: (2020)

MBD2 and MBD3: elusive functions and mechanisms
por: Menafra, Roberta, et al.
Publicado: (2014)

Sex Hormones and Asthma
por: Holguin, Fernando
Publicado: (2020)

Different clinical characteristics of current smokers and former smokers with asthma: a cross-sectional study of adult asthma patients in China
por: Chen, Zhifeng, et al.
Publicado: (2023)

Impact of cinacalcet introduction on MBD management: the MBD-5D study in Japan
por: Fukuma, Shingo, et al.
Publicado: (2013)

MiR‐134‐Mbd3 axis regulates the induction of pluripotency
por: Zhang, Lei, et al.
Publicado: (2016)

Prevention and Treatment of CKD-MBD
por: Cozzolino, Mario
Publicado: (2013)

The Human Proteins MBD5 and MBD6 Associate with Heterochromatin but They Do Not Bind Methylated DNA
por: Laget, Sophie, et al.
Publicado: (2010)

DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells
por: Hainer, Sarah J, et al.
Publicado: (2016)

Recruitment of MBD1 to target genes requires sequence-specific interaction of the MBD domain with methylated DNA
por: Clouaire, Thomas, et al.
Publicado: (2010)

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer
por: Tsuboyama, Natsumi, et al.
Publicado: (2022)

Sex Hormones and Asthma: Don’t Forget Progesterone
por: Lipworth, Brian, et al.
Publicado: (2020)

MBD2 regulates differentiation and function of Th17 cells in neutrophils- dominant asthma via HIF-1α
por: Xu, Li, et al.
Publicado: (2018)

CKD-MBD after kidney transplantation
por: Wesseling-Perry, Katherine, et al.
Publicado: (2011)

A Japanese approach for CKD-MBD
por: Yokoyama, Keitaro, et al.
Publicado: (2013)

The Role of Vitamin K in CKD-MBD
por: Fusaro, Maria, et al.
Publicado: (2022)

CKD-MBD diagnosis: biochemical abnormalities
por: Lucca, Leandro Junior, et al.
Publicado: (2021)

Intragenic MBD5 familial deletion variant does not negatively impact MBD5 mRNA expression
por: Mullegama, Sureni V, et al.
Publicado: (2014)

Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences
por: Günther, Katharina, et al.
Publicado: (2013)

Whole genome MBD-seq and RRBS analyses reveal that hypermethylation of gastrointestinal hormone receptors is associated with gastric carcinogenesis
por: Kim, Hee-Jin, et al.
Publicado: (2018)

Single-nucleus RNA-seq reveals that MBD5, MBD6, and SILENZIO maintain silencing in the vegetative cell of developing pollen
por: Ichino, Lucia, et al.
Publicado: (2022)

Sex and Treatable Traits in Severe Asthma
por: Park, Han-Ki, et al.
Publicado: (2021)

Smek promotes corticogenesis through regulating Mbd3’s stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis
por: Moon, Byoung-San, et al.
Publicado: (2017)

Solution structure of human MBD1 CXXC1
por: Thomson, Ross, et al.
Publicado: (2015)

Clinical significance of parathyroid intervention on CKD-MBD management
por: Ogata, Hiroaki, et al.
Publicado: (2008)

Mbd3 Promotes Reprogramming of Primary Human Fibroblasts
por: Jaffer, Sajjida, et al.
Publicado: (2018)

Germline MBD4 Mutations and Predisposition to Uveal Melanoma
por: Derrien, Anne-Céline, et al.
Publicado: (2020)

Germline mosaicism in a family with MBD5 haploinsufficiency
por: Bhatia, Mehak, et al.
Publicado: (2022)

The Role of Sex Hormones in Pain-Related Conditions
por: Athnaiel, Onella, et al.
Publicado: (2023)

Therapeutic options for severe asthma
por: Mathew, Jilcy, et al.
Publicado: (2012)

Therapeutic interventions in severe asthma
por: Canonica, Giorgio Walter, et al.
Publicado: (2016)

Sex Differences in Severe Asthma: Results From Severe Asthma Network in Italy-SANI
por: Senna, Gianenrico, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i91livvoj3q3gp84b61t4imv7l