CHD5 inhibits metastasis of neuroblastoma

CHD5, a tumor suppressor at 1p36, is frequently lost or silenced in poor prognosis neuroblastoma (NB) and many adult cancers. The role of CHD5 in metastasis is unknown. We confirm that low expression of CHD5 is associated with stage 4 NB. Forced expression of CHD5 in NB cell lines with 1p loss inhib...

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Detalles Bibliográficos
Autores principales: Laut, Astrid K., Dorneburg, Carmen, Fürstberger, Axel, Barth, Thomas F. E., Kestler, Hans A., Debatin, Klaus-Michael, Beltinger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799470/
https://www.ncbi.nlm.nih.gov/pubmed/34789839
http://dx.doi.org/10.1038/s41388-021-02081-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799470/
https://www.ncbi.nlm.nih.gov/pubmed/34789839
http://dx.doi.org/10.1038/s41388-021-02081-0

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