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microRNA-124-3p attenuates myocardial injury in sepsis via modulating SP1/HDAC4/HIF-1α axis

Sepsis-induced cardiac dysfunction can lead to death in sepsis. In this case, we targeted to explore in detail the relative mechanism of microRNA (miR)-124-3p in sepsis-induced myocardial injury via the specific protein 1/histone deacetylase 4/hypoxia-inducing factor 1α (SP1/HDAC4/HIF-1α) axis. Sept...

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Detalles Bibliográficos
Autores principales: Wu, Mei, Huang, Zehong, Huang, Wenfang, Lin, Mengyu, Liu, Weifeng, Liu, Kexuan, Li, Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799658/
https://www.ncbi.nlm.nih.gov/pubmed/35091534
http://dx.doi.org/10.1038/s41420-021-00763-y