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The gut microbial metabolite, 3,4-dihydroxyphenylpropionic acid, alleviates hepatic ischemia/reperfusion injury via mitigation of macrophage pro-inflammatory activity in mice
Hepatic ischemia/reperfusion injury (HIRI) is a serious complication that occurs following shock and/or liver surgery. Gut microbiota and their metabolites are key upstream modulators of development of liver injury. Herein, we investigated the potential contribution of gut microbes to HIRI. Ischemia...
Autores principales: | Li, Rui, Xie, Li, Li, Lei, Chen, Xiaojiao, Yao, Tong, Tian, Yuanxin, Li, Qingping, Wang, Kai, Huang, Chenyang, Li, Cui, Li, Yifan, Zhou, Hongwei, Kaplowitz, Neil, Jiang, Yong, Chen, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799880/ https://www.ncbi.nlm.nih.gov/pubmed/35127379 http://dx.doi.org/10.1016/j.apsb.2021.05.029 |
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